Dual Site-Dual Channel Non-invasive Brain Stimulation for Motor Function in Healthy Subjects

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Device: M1 stimulation; Device: PMC stimulation; Device: Sham stimulation

• Registration Number: NCT03486795
• Lead Sponsor: Samsung Medical Center

Brief Summary

The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of motor function in healthy subjects. Simultaneous dual site-dual channel stimulation was applied by using two sets of transcranial direct current stimulation devices. All subjects will go through four conditions of transcranial direct current stimulation with for 30 minutes. Four conditions are 1) Dual stimulation: i) anodal stimulation on right primary motor cortex and cathodal stimulation on left primary motor cortex, ii) anodal stimulation on right premotor cortex and cathodal stimulation on left supraorbital area. 2) M1 stimulation: anodal stimulation on right primary motor cortex and cathodal stimulation on left primary motor cortex; 3) PMC stimulation: anodal stimulation on right premotor cortex and cathodal stimulation on left supraorbital area. 4) sham stimulation

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2017-10-31
• Status Verified: 2018-03
• Study First Submitted: 2018-03-22
• Study First Submitted QC: 2018-04-01
• Study First Posted: 2018-04-03
• Primary Completion: 2018-05-10
• Study Completion: 2018-05-10
• Last Update Submitted: 2019-09-19
• Last Update Posted: 2019-09-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 27

Inclusion Criteria

• healthy subjects with age over 19 years old

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Exclusion Criteria

• history of disorders involving central nervous system
• patients with severe medial or psychiatric disease

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Dual stimulation	M1 stimulation	1. anodal stimulation on right primary motor cortex and cathodal stimulation on left primary motor cortex 2. anodal stimulation on right premotor cortex and cathodal stimulation on left supraorbital area
M1 stimulation	M1 stimulation	anodal stimulation on right primary motor cortex and cathodal stimulation on left primary motor cortex
PMC stimulation	PMC stimulation	anodal stimulation on right premotor cortex and cathodal stimulation on left supraorbital area
Sham stimulation	Sham stimulation	Sham stimulation

Primary Outcome Measures

Name	Time	Method
Changes in motor evoked potential	Baseline and after intervention (approximately 30 minutes)	measure the motor threshold and amplitude of motor evoked potential in first dorsal interosseous muscle

Secondary Outcome Measures

Name	Time	Method
Changes in sequential motor task	Baseline and after intervention (approximately 30 minutes)	measures motor functional and dexterity of hand

Trial Locations

Locations (1)

Samsung Medical Center; 🇰🇷 Seoul, Korea, Republic of