Vegan Diets: the short-term effects on daily muscle protein synthesis rates as compared to omnivorous diets in Older adults assessed by D2O.
- Conditions
- Sarcopenia
- Registration Number
- NL-OMON26953
- Lead Sponsor
- Wageningen University and research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 24
Aged 65-79 years old; Community-dwelling; BMI 20-35 kg/m2.
-Following a vegetarian or vegan diet during the six months prior to the study;
-Following a diet that affects protein intake during the six months prior to the study;
-Participating in a structured exercise training program in the past three months;
-=5% of body weight loss during three months before the start of the study;
-Being diagnosed with one of the following: diabetes; renal disease; neurological or neuromuscular disorders; serious cardiovascular diseases; cancer; chronic obstructive lung disease (COPD);
-Chronic use of medication that affects muscle function, e.g. corticosteroids, metformin, insulin;
-The use of the following medicines: acenocoumarol (sintrom); phenprocoumon (marcoumar); dabigatran (pradaxa); apixaban (eliquis); rivaroxaban (xarelto); clopidogrel (plavix); combination of acetylsalicylic acid or carbasalate calcium (ascal) with dipyridamole.
-Allergic or intolerant to any product included in the diets;
-Not willing to stop nutritional supplements, with the exception of supplements on medical advice, and vitamin D;
-Not willing or afraid to give blood or undergo a muscle biopsy during the study;
-Unwilling to eat a vegan and an omnivorous diet for ten days each;
-Not vaccinated for COVID-’19;
-Currently a research participant in another trial or participated in a clinical trial during three months before the start of the measurement period;
-Not being able to understand Dutch;
-Not having a general physician.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method