Impact of E-cigarette Characteristics on Reinforcement and Tobacco Use Patterns

Not Applicable

Completed

• Conditions: Smoking; Tobacco Use
• Interventions: Behavioral: Low Power; Behavioral: High Power; Behavioral: High Concentration; Behavioral: Low Concentration

• Registration Number: NCT03844672
• Lead Sponsor: Medical University of South Carolina

Brief Summary

The purpose of this project is to understand how different e-cigarettes influence their likeability and use among current smokers who try using e-cigarettes. Participants will receive an e-cigarette to sample over a three week period. During this time period they will complete daily electronic diaries and weekly lab visits. The results from this information will help understand how different types of e-cigarettes are likely to influence cigarette and e-cigarette use.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study First Submitted: 2019-02-14
• Study First Submitted QC: 2019-02-14
• Study First Posted: 2019-02-18
• Study Start: 2019-04-01
• Primary Completion: 2023-10-17
• Study Completion: 2023-11-09
• Results First Submitted: 2024-09-26
• Status Verified: 2024-10
• Results First Submitted QC: 2024-10-22
• Last Update Submitted: 2024-10-22
• Results First Posted: 2024-10-24
• Last Update Posted: 2024-10-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 93

Inclusion Criteria

Not provided

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Exclusion Criteria

Not provided

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
High Concentration / Low Power	High Concentration	Participant will receive an e-liquid with a high nicotine concentration and an e-cigarette with a low power for three weeks.
High Concentration / High Power	High Concentration	Participant will receive an e-liquid with a high nicotine concentration and an e-cigarette with a high power for three weeks.
Low Concentration / Low Power	Low Power	Participant will receive an e-liquid with a low nicotine concentration and an e-cigarette with a low power for three weeks.
Low Concentration / High Power	High Power	Participant will receive an e-liquid with a low nicotine concentration and an e-cigarette with a high power for three weeks.
Low Concentration / High Power	Low Concentration	Participant will receive an e-liquid with a low nicotine concentration and an e-cigarette with a high power for three weeks.
High Concentration / Low Power	Low Power	Participant will receive an e-liquid with a high nicotine concentration and an e-cigarette with a low power for three weeks.
High Concentration / High Power	High Power	Participant will receive an e-liquid with a high nicotine concentration and an e-cigarette with a high power for three weeks.
Low Concentration / Low Power	Low Concentration	Participant will receive an e-liquid with a low nicotine concentration and an e-cigarette with a low power for three weeks.

Primary Outcome Measures

Name	Time	Method
Mean Cigarettes Per Day	Week 3	Participants complete weekly surveys reporting the number of cigarettes smoked each day on a continuous scale

Secondary Outcome Measures

Name	Time	Method
Average Number of E-cigarette Puffing Episodes	Week 3	Participants complete weekly surveys reporting the number of e-cigarette puffing episodes each day on a continuous scale
Number of Choices to Smoke Cigarette in Lab Setting	Week 3	Participants complete lab-based choice task at Week 3 visit in which they choose between smoking conventional cigarette and e-cigarette over 10 trials. Outcome is number of times each participant chooses to smoke conventional cigarette.

Trial Locations

Locations (1)

Medical University of South Carolina; 🇺🇸 Charleston, South Carolina, United States