The Effects of Intraoperative Dexmedetomidine Infusion on Postoperative Bowel Movement in Patients Undergoing Laparoscopic Gastrectomy
Phase 4
Completed
- Conditions
- Gastric Cancer Patients Undergoing Laparoscopic Gastrectomy
- Interventions
- Drug: the control groupDrug: the dexmedetomidine group
- Registration Number
- NCT02164448
- Lead Sponsor
- Yonsei University
- Brief Summary
The investigators hypothesized that sympatholytic effect of dexmedetomidine would attenuate the hemodynamic instability and decrease in the splanchnic blood flow caused by pneumoperitoneum during laparoscopic surgery. This study is to investigate the effect of intraoperative dexmedetomidine infusion on postoperative bowel movement in patients undergoing laparoscopic gastrectomy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 92
Inclusion Criteria
- patient between 20 and 65 of age with ASA physical status Ⅰ-Ⅲ
- gastric cancer patient undergoing laparoscopic gastrectomy
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Exclusion Criteria
- ASA physical status Ⅳ
- bradycardia (< 60 bpm), arrhythmia
- uncompensated heart failure
- hepatic failure (Child-Pugh score B 이상)
- renal failure (eGFR MDRD < 60 ml/min/1.73m2)
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description control group the control group - dexmedetomidine group the dexmedetomidine group -
- Primary Outcome Measures
Name Time Method gas passing up to 1 week To evaluate the postoperative bowel movement, we will assess the time to first gas passing
- Secondary Outcome Measures
Name Time Method sips of water time up to 1 week To evaluate the postoperative bowel movement, we will assess the time to resume water intake
Trial Locations
- Locations (1)
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine,
🇰🇷Seoul, Korea, Republic of