Acute effects of consuming a single high fat meal alone, cocoa alone, or consuming both a high fat meal with a cocoa drink on antioxidants, oxidative stress and inflammatory cytokines in healthy human volunteers

Completed

• Conditions: Changes to antioxidant status, oxidative stress markers and inflammatory cytokine levels (all in circulation) in response to an unhealthy (high fat) meal; Diet and Nutrition - Other diet and nutrition disorders; Inflammatory and Immune System - Other inflammatory or immune system disorders

• Registration Number: ACTRN12612000058875
• Lead Sponsor: Deakin University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-01-11
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

young age (18y-35y), good health (no known illnesses that will affect study, healthy BMI, healthy blood pressure, healthy glucose range, healthy for blood biochemistry markers), not taking supplements / antioxidants / drugs that would interfere with study measures, willing to volunteer, willing to undergo blood tests, lack of allergies to test foods, non-elite athlete / not undertaking large amounts of exercise, not pregnant, does not have blood disorders, and has not been diagnosed with any condition that may affect results.

Exclusion Criteria

Outside of the target age, poor health parameters (illnesses known to affect the primary measures of the study, BMI outside of the healthy range, high or low blood pressure, blood glucose outside of the healthy range, abnormalities in blood lipid levels), taking supplements / antioxidants (large amounts) / drugs / medications known to alter study measures, allergies to foods in test meals, not willing to undergo blood sampling, elite athlete / undertaking heavy exercise, pregnancy / attempting to become pregnant, have a blood clotting or other blood disorder, or have been diagnosed with a condition known to affect study measurements.

Study & Design

• Study Type: Interventional
• Study Design: Not specified