A comparative study of multimodal analgesia with thoracic epidural for laparotomy
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- 1)To estimate the time of request of first rescue analgesic
研究概览
简要总结
A double-blinded, prospective study with hundred patients will be divided randomly into two groups of fifty each: Group E will be given epidural analgesia, Group M will be given multimodal analgesia for their post-laparotomy period. Both the groups will be monitored for 48 hours postoperatively. The parameters recorded will be blood pressure, pulse rate, saturation, visual analog scale for pain scores every hour. Whenever the visual analog score crosses 4, patients will be given rescue analgesic. The total number of rescue analgesics required in both groups will be recorded for 48 hours postoperatively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA I & II PATIENTS SURGERY DURATION WITHIN 4 HOURS.
排除标准
- •KNOWN ALLERGY/HYPERSENSITIVITY TO DRUGS USED LOCAL SKIN SITE INFECTION COAGULOPATHY PRE-EXISTING ACUTE/CHRONIC PAIN PREVIOUS ABDOMINAL SURGERIES PATIENTS WITH SIGNIFICANT CARDIAC, PULMONARY, HEPATIC DISEASES.
结局指标
主要结局
1)To estimate the time of request of first rescue analgesic
时间窗: 48 hours
2) To estimate the total dose of rescue analgesic consumed in the early postoperative period
时间窗: 48 hours
次要结局
- To estimate the incidence of hypotension, nausea and vomiting(48 hours)