Impact of personalized low glycemic nutrition as compared to standard dietary recommendations (based on the German nutrition society, DGE) on skin conditions in acne patients and healthy controls with oily ski
Not Applicable
Recruiting
- Conditions
- L70Acne
- Registration Number
- DRKS00018946
- Lead Sponsor
- Beiersdorf AG, Front End InnovationManager Gut-to-Skin Axis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 390
Inclusion Criteria
Knowledge of German language
Android- or iOS-Smartphones
all sexes
Acne: clinically proben (facial Acne papulopustulosa or Acne papulopustulosa et comedonica), mild to moderate (Grade 2 - 8 according Leeds Scale of Acne Grading), al least 10 inflammatory lesions, no treatment other than OTC
control group: healthy skin of all types
Exclusion Criteria
medical acne treatment
antibiotics
pre- or probiotics
pregnancy, breast feeding
underweight or obesity (BMI < 18,5 kg/m2, BMI = 30 kg/m2)
inflammatory skin condition other than acne
intestinal diseases
malignant diseases
Type 1 and Type 2 Diabetes mellitus
food intolerance/allergies
autoimmune diseases
eating disorders
drug addiction
shift work
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Acne: Improvement of skin determined by: i) inflammatory lesions (face), ii) acne score, iii) sebum quantity and quality (before and after nutrition intervention)<br>Skin healthy individuals: Improvement of skin determined by: i) self assessment. ii) sebum quantity and quality (before and after nutrition intervention)
- Secondary Outcome Measures
Name Time Method Applicability of personalized, low-glycemic nutrition advice in treatment of acne patients and other acne-relevant parameters to quantify impact on skin; inflammatory parameters (lipids, immense cells, growth hormones in blood), microbiome before and after nutrition intervention, self assessment with relation to skin and wellbeing