Efficacy of laryngeal anesthesia with a double-lumen airway route topical anesthesia for intubation stress
Not Applicable
- Conditions
- Patients with lung surgery
- Registration Number
- ChiCTR2400089006
- Lead Sponsor
- Anhui Provincial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Age 18~75 years old;<br>2) ASA: I~III level;<br>3) Patients undergoing thoracic surgery who are going to undergo double-lumen bronchial intubation;<br>4) Agree to participate in the clinical study and sign the informed consent form.<br>
Exclusion Criteria
- predict difficult airway.<br>2) allergy to topical anesthesia or other anesthetics.<br>3) severe arrhythmias, such as HR=50 bpm at rest, conduction block (double bundle branch block, second- or third-degree block), frequent premature ventricular contractions, QTc: =450 ms for males, =470 ms for females.<br>4) poorly controlled hypertension (sitting systolic blood pressure (SBP) = 160 mmHg and/or sitting diastolic blood pressure (DBP) =100 mmHg) taking antihypertensive drugs).<br>5) Severe heart and brain organic lesions, severe liver and kidney dysfunction and endocrine diseases.<br>6) Patients with psychiatric illness, long-term use of psychotropic drugs, or cognitive dysfunction judged to be lacking the ability to give informed consent.<br>7) Pregnant or lactating patients.<br>8) Other patients who are considered by the investigators to be unsuitable to participate in this program.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of reactive tachycardia (>120bpm).;Incidence of reactive hypertension (> basal value 130%);
- Secondary Outcome Measures
Name Time Method Heart rate;Mean arterial pressure;Choking;Hoarseness and sore throat;Incidence of respiratory-related complications (atelectasis, hypoxemia, pulmonary infection).;