Cukurova University Faculty of Medicine
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 120
- 主要终点
- the presence of postoperative delirium as defined by CAM criteria.
研究概览
简要总结
The aim of this study is to compare the risk factors and the incidence of delirium following orthopedic surgery under the general or regional anesthesia in elderly patients.
详细描述
One hundred twenty elderly patients aged ≥65 years scheduled for total hip or knee arthroplasty and femur fracture surgery were enrolled into the study. Patients were allocated into two groups to receive regional anesthesia (group R, n=50) or general anesthesia (group G, n=70). Hemodynamic and blood parameters, potential risk factors of delirium including age, sex, duration of surgery, the type of anesthesia, coexisting disease, smoking and amount of drug used delirium tests (CAM and DRS-R-98), hospital stay and costs were recorded for all patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •American Society of Anesthesiologists physical status I-III,
- •120 patients aged ≥65 years scheduled for total hip or knee arthroplasty and femur fracture surgery
排除标准
- •Exclusion criteria were patient refusal, abuse of alcohol and/or drugs
- •Hypersensitivity to local anesthetics
- •Vertebral abnormality
- •Previous lumbar vertebra surgery
- •Coagulation disorder
- •Infection (systemic or local)
- •Cerebrovascular disease
- •Neurosurgery
- •Vascular surgery
- •Frequent use of analgesic drug
- •≥5 drugs per day and psychiatric medication
结局指标
主要结局
the presence of postoperative delirium as defined by CAM criteria.
时间窗: one year
次要结局
- length of hospital stay and costs.(one year)
- severity of delirium rated with the DRS-R-9(one year)
研究者
ILKE KUPELI
specialist dr
Cukurova University