Prevalence of Postoperative Delirium According to the Use of Dexmedetomidine or Propofol in Elderly Patients Undergoing Orthopedic Surgery: Retrospective Study
Overview
- Phase
- N/A
- Intervention
- Dexmedetomidine
- Conditions
- Orthopedics
- Sponsor
- Seoul National University Bundang Hospital
- Enrollment
- 855
- Locations
- 1
- Primary Endpoint
- delirium
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
Delirium are common after orthopedic surgery in the elderly and are directly associated with loss of independence, reduction in the quality of life and increased mortality. The cause of postoperative delirium still remains unclear and may be multifactorial. The aim of this retrospective study is to examine prevalence of postoperative delirium according to the use of dexmedetomidine or propofol in elderly patients undergoing orthopedic surgery under regional anesthesia.
Investigators
Hyo-Seok Na
Associate Professor
Seoul National University Bundang Hospital
Eligibility Criteria
Inclusion Criteria
- •Patients who underwent orthopedic surgery under regional anesthesia
- •age of 65 years or greater
Exclusion Criteria
- •General anesthesia
- •age \< 65 years
- •central nervous system disease, including dementia and Parkinson's disease
- •Patients who were not received sedation with propofol or dexmedetomidine during the operation
Arms & Interventions
DEX
patients who received dexmedetomidine during the operation
Intervention: Dexmedetomidine
PPF
patients who received propofol during the operation
Intervention: Propofol
Outcomes
Primary Outcomes
delirium
Time Frame: within 7 day postoperatively
Secondary Outcomes
- Pulmonary thromboembolism(within 7 day postoperatively)
- Hospital stay(through study completion, an average of 7days)
- Wound infection(within 7 day postoperatively)