NCT02573558已完成不适用
Prevalence of Postoperative Delirium According to the Use of Dexmedetomidine or Propofol in Elderly Patients Undergoing Orthopedic Surgery: Retrospective Study
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 855
- 试验地点
- 1
- 主要终点
- delirium
研究概览
简要总结
Delirium are common after orthopedic surgery in the elderly and are directly associated with loss of independence, reduction in the quality of life and increased mortality. The cause of postoperative delirium still remains unclear and may be multifactorial. The aim of this retrospective study is to examine prevalence of postoperative delirium according to the use of dexmedetomidine or propofol in elderly patients undergoing orthopedic surgery under regional anesthesia.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who underwent orthopedic surgery under regional anesthesia
- •age of 65 years or greater
排除标准
- •General anesthesia
- •age < 65 years
- •central nervous system disease, including dementia and Parkinson's disease
- •Patients who were not received sedation with propofol or dexmedetomidine during the operation
研究组 & 干预措施
DEX
patients who received dexmedetomidine during the operation
干预措施: Dexmedetomidine (Drug)
PPF
patients who received propofol during the operation
干预措施: Propofol (Drug)
结局指标
主要结局
delirium
时间窗: within 7 day postoperatively
次要结局
- Pulmonary thromboembolism(within 7 day postoperatively)
- Hospital stay(through study completion, an average of 7days)
- Wound infection(within 7 day postoperatively)
研究者
Hyo-Seok Na
Associate Professor
Seoul National University Bundang Hospital
研究点 (1)
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