Brain-gut interaction mechanism of Yan Nian Jiu Zhuan method in CFS intervention based on fMRI brain functional connectivity density

Phase 1

• Conditions: chronic fatigue syndrome

• Registration Number: ITMCTR2200006154
• Lead Sponsor: Shanghai Municipal Hospital of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

(1) Aged between 20-60 years old, no gender requirement;
(2) Those with no abnormality in blood, urine routine tests and liver and kidney functions;
(3) Those who have not received any other treatment options within 1 month;
(4) Those who agree and sign the informed consent form.

Exclusion Criteria

(1) Patients with severe cardiovascular and cerebrovascular diseases, endocrine system diseases, motor system diseases, autoimmune diseases
Disease patients, infectious diseases;
(2) Those who take drugs that may affect the judgment of the results;
(3) No complaints of fatigue or diagnosis of acute or chronic diseases;
(4) Unwilling to join the researcher;
(5) Pregnant or lactating women, drug addiction, heavy metal poisoning, etc.
(6) Taking large doses of medicines recently, taking medicines, health products, drinking alcohol within 24 hours before the test,
Those who eat spicy and other irritating foods.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Multi-dimensional Fatigue Inventory 20;

Secondary Outcome Measures

Name	Time	Method
peripheral blood;Hospital Anxiety and Depression Scale;gut microbiota;short form 36;Gastrointestinal Symptom Rating Scale;TCM Clinical Symptom Diagnosis Scale;fMRI;Tongue and pulse diagnostic apparatus;