C-reactive protein assisted prescribing for respiratory tract infections to stimulate Antibiotic stewardship; a randomised controlled trial in general practice.
Recruiting
- Conditions
- 1. Lower respiratory tract infections (LRTI)<br /> 2. rhinosinusitis<br /> 3. general practice<br />4. antibiotics<br />(Luchtweginfecties, huisartspraktijk,antibiotica).
- Registration Number
- NL-OMON29094
- Lead Sponsor
- niversity of MaastrichtCare and Public Health Research InstitutePO Box 6166200 MD MaastrichtThe Netherlands
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 200
Inclusion Criteria
The GPs will include adult patients (>=18 years) with acute LRTI or rhinosinusitis during normal consultation hours. The patient must meet the inclusion criteria listed below.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Prescribing rates at index consultation (day 0), defined as immediate, delayed or no antibiotics.
- Secondary Outcome Measures
Name Time Method Secondary study parameters/outcome of the study (if applicable):<br /><br>1. Total antibiotic exposure over a period of 28 days, defined as the number of patients receiving immediate antibiotics or filling a delayed prescription for antibiotics within 28 days of index consultation (day 0);<br /><br>2. Clinical recovery;<br /> <br>3. Patient satisfaction and enablement;<br /> <br>4. Reconsultation within 28 days;<br /><br>5. Evaluation of GPs' estimation of CRP value based on usual diagnostic work-up (medical history and physical examination) compared to actual CRP test result;<br /><br>6. CRP value on day 0 and day 7 in relation to perceived degree of illness (VAS, Visual Analogue Scale). <br><br>