Preemptive Analgesia With Intravenous Paracetamol for Post-cesarean Section Pain Control : A Randomized Controlled Trial
Overview
- Phase
- Phase 4
- Intervention
- paracetamol
- Conditions
- Cesarean Section; Dehiscence
- Sponsor
- Baskent University
- Enrollment
- 60
- Primary Endpoint
- Postoperative pain scores measured by visual analog scale (VAS)
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
The investigators designed a prospective randomized study to investigate the efficacy of intravenous (IV) preemptive paracetamol on postoperative pain scores, patient satisfaction, total morfin consumption and the incidence of morfin-related side effects in patients undergoing cesarean section.
Investigators
Ozlem Ozmete
Medical Doctor
Baskent University
Eligibility Criteria
Inclusion Criteria
- •Patients between the ages of 20-40 years,
- •ASA physical status 1-2 who underwent elective cesarean surgery during general anesthesia were included in the study
Exclusion Criteria
- •A history of allergy to any of the study medications (opiod, general anesthetic agents or paracetamol),
- •history of opioid or paracetamol use,
- •hepatic or renal failure,
- •any psychological disorders,
- •complications during cesarean section and unable to use PCIA device were excluded from the study.
Arms & Interventions
Group Paracetamol (Group P),
Drugs were given intravenously by a nurse unaware of the study 15 min before surgery. Patients in group P (n = 30) received 1 g iv paracetamol
Intervention: paracetamol
Group Saline (Group S)
Drugs were given intravenously by a nurse unaware of the study 15 min before surgery. Patients in group S (n = 30) received 100 ml iv %0,9 saline
Intervention: Placebo
Outcomes
Primary Outcomes
Postoperative pain scores measured by visual analog scale (VAS)
Time Frame: Postoperative 24 hours