Preemptive Analgesia With Intravenous Paracetamol for Post-cesarean Section Pain Control : A Randomized Controlled Trial
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 60
- 主要终点
- Postoperative pain scores measured by visual analog scale (VAS)
研究概览
简要总结
The investigators designed a prospective randomized study to investigate the efficacy of intravenous (IV) preemptive paracetamol on postoperative pain scores, patient satisfaction, total morfin consumption and the incidence of morfin-related side effects in patients undergoing cesarean section.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Care Provider, Investigator)
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Patients between the ages of 20-40 years,
- •ASA physical status 1-2 who underwent elective cesarean surgery during general anesthesia were included in the study
排除标准
- •A history of allergy to any of the study medications (opiod, general anesthetic agents or paracetamol),
- •history of opioid or paracetamol use,
- •hepatic or renal failure,
- •any psychological disorders,
- •complications during cesarean section and unable to use PCIA device were excluded from the study.
研究组 & 干预措施
Group Paracetamol (Group P),
Drugs were given intravenously by a nurse unaware of the study 15 min before surgery. Patients in group P (n = 30) received 1 g iv paracetamol
干预措施: paracetamol (Drug)
Group Saline (Group S)
Drugs were given intravenously by a nurse unaware of the study 15 min before surgery. Patients in group S (n = 30) received 100 ml iv %0,9 saline
干预措施: Placebo (Drug)
结局指标
主要结局
Postoperative pain scores measured by visual analog scale (VAS)
时间窗: Postoperative 24 hours
次要结局
未报告次要终点
研究者
Ozlem Ozmete
Medical Doctor
Baskent University