Rebreathing of Carbon Dioxide With a Device Used for Giving Inhalational Anaesthesia

Not Applicable

Completed

• Conditions: Anesthetic Ventilatory Requirements
• Interventions: Device: Anesthetic Conserving Device (AnaConDa )

• Registration Number: NCT01339013
• Lead Sponsor: Region Skane

Brief Summary

The anesthesia gas reflector (AnaConDa) is built on the adsorptive capacity of active carbon which also adsorbs carbon dioxide in exhaled air. Rebreathing of carbon dioxide thus occurs and must be compensated for by increased ventilation. This study aims at determining how much compensation must be given, based on the hypothesis that rebreathing depends on carbon dioxide level in blood and exhaled air.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-04
• Study First Submitted: 2011-04-13
• Study First Submitted QC: 2011-04-19
• Study First Posted: 2011-04-20
• Primary Completion: 2013-01
• Study Completion: 2013-01
• Results First Submitted: 2014-03-14
• Status Verified: 2014-09
• Results First Submitted QC: 2014-09-10
• Results First Posted: 2014-09-11
• Last Update Submitted: 2014-09-12
• Last Update Posted: 2014-09-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 6

Inclusion Criteria

• elective coronary artery by-pass graft surgery
• elective valve replacement surgery
• normal left ventricular ejection fraction on preoperative echocardiography

Exclusion Criteria

• obstructive lung disease
• restrictive lung disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
AnaConDa	Anesthetic Conserving Device (AnaConDa )	-

Primary Outcome Measures

Name	Time	Method
Airway Dead Space With Devices for Heat and Moisture Exchange of Respiratory Gas.	1 hour	A conventional heat and moisture exchanger used in a respiratory circuit during anasthesia was exchanged by an AnaConDa. The AnaConDa causes re-breathing of carbon dioxide which clinically is equivalent to an increased airway dead space. The total airway dead space effect of the AnaConDa, i.e. volume of the device plus rebreathing from the charcoal filter was measured using the Single Breath Test for carbon dioxide, as was airway deadspace of the conventional Heat and Moisture Exchanger. Airway dead space differences between devices was calculated by subtraction of volumes thus achieved. Difference= Airway dead space AnaConDa - Airway dead space conventional Heat and Moisture Exchanger.

Trial Locations

Locations (1)

University Hospital, Cardiothoracic Intensive Care; 🇸🇪 Lund, Sweden