A Observational Study to Compare Effectiveness and Safety of the Surgeries in Patients With Esophageal Cancer
- Conditions
- Esophageal Cancer
- Registration Number
- NCT03428074
- Lead Sponsor
- Chinese PLA General Hospital
- Brief Summary
The study was designed to compare effectiveness and safety of the surgeries of Ivor-Lewis and Mckeown in patients with esophageal cancer
- Detailed Description
The trial is a multi-centre real-world non-interventional observational study. The study was designed to compare effectiveness and safety of the minimally invasive surgeries of Ivor-Lewis and Mckeown in the Chinese patients with IA-IIIB esophageal cancer via a retrospectively review method based on the study data on patient demographic/tumor biological characteristics and clinical treatments.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1862
- Pathologically diagnosed middle and lower thoracic IA-IIIB esophageal cancer after surgeries;
- Patients who received minimally invasive radical dissections of Ivor-Lewis and Mckeown;
- Patients who received tubular gastroesophageal reconstruction;
- Patients complicated with arrhythmia, or serious disfunctions of heart, lung, liver, and kidney before surgeries;
- Patients with second primary tumors;
- Patients who received abdominal or thoracic surgeries;
- Patients who received gastrostomy or nesteostomy before surgeries;
- Patients with suspected cervical lymph metastases (in the subgroup of the patients who received the surgery of Mckeown)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Overall survivals in patients with esophageal cancer who received surgeries 2010 - 2017 Overall survivals in patients with esophageal cancer who received surgeries categorised by tumor biological characteristics
- Secondary Outcome Measures
Name Time Method Death rates within 30 days after surgeries 2010 - 2017 Death rates within 30 days after surgeries categorised by tumor biological characteristics
Trial Locations
- Locations (9)
China-Japan Friendship Hospital
🇨🇳Beijing, Beijing, China
Henan cancer hospital
🇨🇳Zhengzhou, Henan, China
Tongji Hospital Affiliated to Huazhong Technology Hospital
🇨🇳Wuhan, Hubei, China
Jiangsu Cancer Hospital
🇨🇳Nanjing, Jiangsu, China
Xi'an Tangdu Hospital
🇨🇳Xi'an, Shaanxi, China
Shanghai Chest Hospital
🇨🇳Shanghai, Shanghai, China
Huaxi Hospital Affiliated to Sichuan University
🇨🇳Chengdu, Sichuan, China
Tianjin Chest Hospital
🇨🇳Tianjin, Tianjin, China
First Hospital Affiliated to Medical College, Zhejiang University
🇨🇳Hangzhou, Zhejiang, China
China-Japan Friendship Hospital🇨🇳Beijing, Beijing, China