A Multi-centre Real-world Non-interventional Observational Study to Compare Effectiveness and Safety of the Minimally Invasive Surgeries of Ivor-Lewis and Mckeown in Chinese Patients With IA-IIIB Esophageal Cancer
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Esophageal Cancer
- Sponsor
- Chinese PLA General Hospital
- Enrollment
- 1862
- Locations
- 9
- Primary Endpoint
- Overall survivals in patients with esophageal cancer who received surgeries
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
The study was designed to compare effectiveness and safety of the surgeries of Ivor-Lewis and Mckeown in patients with esophageal cancer
Detailed Description
The trial is a multi-centre real-world non-interventional observational study. The study was designed to compare effectiveness and safety of the minimally invasive surgeries of Ivor-Lewis and Mckeown in the Chinese patients with IA-IIIB esophageal cancer via a retrospectively review method based on the study data on patient demographic/tumor biological characteristics and clinical treatments.
Investigators
Yang Liu
Professor
Chinese PLA General Hospital
Eligibility Criteria
Inclusion Criteria
- •Pathologically diagnosed middle and lower thoracic IA-IIIB esophageal cancer after surgeries;
- •Patients who received minimally invasive radical dissections of Ivor-Lewis and Mckeown;
- •Patients who received tubular gastroesophageal reconstruction;
Exclusion Criteria
- •Patients complicated with arrhythmia, or serious disfunctions of heart, lung, liver, and kidney before surgeries;
- •Patients with second primary tumors;
- •Patients who received abdominal or thoracic surgeries;
- •Patients who received gastrostomy or nesteostomy before surgeries;
- •Patients with suspected cervical lymph metastases (in the subgroup of the patients who received the surgery of Mckeown)
Outcomes
Primary Outcomes
Overall survivals in patients with esophageal cancer who received surgeries
Time Frame: 2010 - 2017
Overall survivals in patients with esophageal cancer who received surgeries categorised by tumor biological characteristics
Secondary Outcomes
- Death rates within 30 days after surgeries(2010 - 2017)