Insulin sensitivity in adults with a mitochondrial disorder.

Recruiting

• Conditions: diabetes mellitus and mitochondrial disorder; 10018424; 10021605

• Registration Number: NL-OMON32965
• Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 14

Inclusion Criteria

Adult patients with an inborn mitochondrial disorder due to a defect in the oxidative phosphorylation (OXPHOS).

Exclusion Criteria

diabetes mellitus, mental retardation or the use of drugs that influence glucose metabolism.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The insulin sensitivity index (Mi-value) is used to kwantify insulin<br /><br>sensitivity. A difference of more than 30% between the patients and the control<br /><br>group is considered clinically relevant. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable</p><br>