Comparison of two types of treatment which cause short acting muscle relaxation to determine which treatment allows patients to resume normal breathing in the shortest period of time
Not Applicable
Completed
- Conditions
- Routine general anaesthesiaSurgeryAnaesthesia
- Registration Number
- ISRCTN18103747
- Lead Sponsor
- Belfast Health and Social Care Trust (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
1. American Society of Anaesthesiologists (ASA) class I - III
2. Patients able to give written informed consent
3. Patients requiring general anaesthesia
4. Patients aged 18 - 65 years, either sex
Exclusion Criteria
1. History of dementia or difficulty in providing informed consent
2. Patients with chronic obstructive pulmonary disease (COPD)
3. Patients with a history of ischaemic heart disease (IHD)
4. Patients with a haemoglobin concentration of less than 10 g/dl
5. Patients with a history of known difficulty in intubation or with an anticipated challenging airway
6. Pregnancy
7. Patients with a history of allergy to any of the medications used in the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ength of time to resumption of spontaneous ventilation as indicated by visible diaphragmatic movement or decrease in oxygen saturation to less than or equal to 90% before onset of spontaneous ventilation
- Secondary Outcome Measures
Name Time Method 1. Frequency of desaturation to less than or equal to 90%<br>2. Length of time to movement of reservoir bag<br>3. Length of time to first capnographic evidence of ventilation<br>4. Incidence of adverse events in all groups