Oxygen Preconditioning Prevents Contrast-Induced Nephropathy - OPtion CI

Yokohama Medical Center (Department of Clinical Research)0 sites400 target enrollmentJanuary 24, 2012

ConditionsIschemic Heart Disease Congestive Heart Failure Chronic Kidney Disease Peripheral arterial Disease

Overview

Phase: 未知
Intervention: Not specified
Conditions: Ischemic Heart Disease Congestive Heart Failure Chronic Kidney Disease Peripheral arterial Disease
Sponsor: Yokohama Medical Center (Department of Clinical Research)
Enrollment: 400
Status: Completed
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

The patient in the oxygen preconditioning group had significantly higher PaO2 (134.3 +- 27.7 vs. 90.1 +- 11.7 mmHg, P < 0.01) and significantly lesser incidence of CIN (0.6% vs. 6.1%, odds ratio 0.10, P = 0.01, 95% CI 0.01-0.75) comparing with those in the control group.

Registry

who.int

Start Date

January 24, 2012

End Date

August 1, 2011

Last Updated

2 years ago

Study Type

Interventional

Sex

All

Investigators

Sponsor

Yokohama Medical Center (Department of Clinical Research)

Eligibility Criteria

Inclusion Criteria

Not provided

Exclusion Criteria

•peritoneal dialysis, hemodialysis treatment, cardiogenic shock, congestive heart failure, pregnancy, a history of severe allergies to contrast media, recent major bleeding, having a metformin within 48 hours of the study entry, chronic obstructive pulmonary disease, patient with the oxygen saturation lesser than 90 percent, acute coronary syndrome, severe infection, severe malnutrition, post\-operative states, pituitary or adrenal dysfunction, paraquat intoxication