Does Vnotes Salpingectomy Reduce Ovarian Reserve?

Not Applicable

• Conditions: Vnotes; Salpingectomy; Ovarian Reserve

• Registration Number: NCT07177144
• Lead Sponsor: Gaziosmanpasa Research and Education Hospital

Brief Summary

Comparison of Transvaginal Natural Orifice Transluminal Endoscopic Surgery and Conventional Laparoscopy in terms of their effects on ovarian reserve in Opportunistic Bilateral Salpingectomy for Permanent Female Sterilization

Detailed Description

The study will include participants who apply to our clinic for salpingectomy for contraception and agree to participate in the study. vnotes salpingectomy method or classical laparoscopic salpingectomy will be offered to the patients as two salpingectomy methods and the patient will be included in whichever group in the study. All surgeries will be performed by the same surgeon. 3 months after the date of surgery, the patient will be called for a follow-up for amh repeat and the two groups will be compared both within themselves and with each other to evaluate whether the different surgical technique has an effect on ovarian reserve.

Study Timeline

• Study Start: 2025-06-19
• Status Verified: 2025-08
• Study First Submitted: 2025-08-18
• Study First Submitted QC: 2025-09-12
• Last Update Submitted: 2025-09-12
• Study First Posted: 2025-09-16
• Last Update Posted: 2025-09-16
• Primary Completion: 2025-09-30
• Study Completion: 2025-09-30

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: Female
• Target Recruitment: 46

Inclusion Criteria

• to want to have your tubes removed, not to have undergone tubal and ovarian surgery before, not to use hormones and medications that can affect the level of sex hormones and its levels,

Exclusion Criteria

• not being in the specified age range (18-45), having a history of tubal ligation, having tubal cancer

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
measuring anti-millerian hormone level	amh level (ng/ml) will be checked before the operation, and after 3 months, she will be called for control and measured again.	To evaluate the effect of two surgical methods on ovarian reserve by measuring serum anti-Müllerian hormone levels (ng/ml) before surgery and after salpingectomy.

Secondary Outcome Measures

Name	Time	Method
comparison of duration of surgery	Perioperative	To compare the success of the two surgical techniques Surgery duration: the time from when the patient first receives anesthesia until they are awakened, recorded in minutes (min)
Postoperative hospital stay duration	Perioperative	The days the patient stays in the hospital, starting from the first day they are admitted for surgery until they are discharged after full recovery following the surgery, will be recorded as days. the number of days the patient stays in the hospital, recorded in days (days)
postoperative pain	first hour after surgery	The patient is asked to rate the pain they feel from the moment they wake up after surgery on a scale of 1 to 10.

Trial Locations

Locations (1)

Gaziosmanpaşa Education and Research Hospital; Istanbul, Turkey (Türkiye)