PETscan imaging for objectivation of cortical hyperactivity in tinnitus patients
Recruiting
- Conditions
- noise in the headtinnitus1002239610042258
- Registration Number
- NL-OMON31403
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
Chronic tinnitus, > 3 months, perceived in the head, not lateralized, constant in presence. Right-handed
Exclusion Criteria
Presence of any major medical, neurological or psychiatric diagnoses now or in the past, specific epilepsy, severe head injury or previous cranial neurosurgery. Participation in a PET study in the year prior to this study. Radiological workers. Use of drugs or medications that reduce cortical excitation such as anticonvulsants, benzodiazepines or other sedatives. Pregnancy.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study parameter will be the cortical hyperactivity in tinnitus<br /><br>patients compared to control subjects in FDG-PET, analysed with SPM5. Our<br /><br>estimation is that this cortical hyperactivity is localised in the primary<br /><br>auditory cortex and the associative auditory cortex, although other regions<br /><br>might display some hyperactivity as well</p><br>
- Secondary Outcome Measures
Name Time Method <p>Not applicable</p><br>