Comparing the effects of Dexmedetomidine and Metoprolol and Magnesium Sulphate in ReducingBlood Loss during Craniotomy
Phase 3
Recruiting
- Conditions
- Craniotomy surgery.CraniorachischisisQ00.1
- Registration Number
- IRCT20141209020258N188
- Lead Sponsor
- Arak University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 99
Inclusion Criteria
Age 18 to 75 years
ASA class Iand II
Absence of coagulation disorders
No history of cardiovascular diseases
Proper control of blood pressure
Absence of pregnancy
No addiction to opioids
Body mass index less than 35
Craniotomy candidate patients
Having consent to enter the study
Absence of sensitivity to the study drugs
The presence of creatinine less than 1/5
Absence of platelet count less than 150 thousand
Serum magnesium is less than or equal to 2.5
Exclusion Criteria
Dissatisfaction
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Average hemoglobin. Timepoint: Before and 12 hours after surgery. Method of measurement: Blood test.;Bleeding. Timepoint: during surgery. Method of measurement: Based on scoring 1 to 4 bleeding volume.;Consent of the surgeon. Timepoint: After surgery. Method of measurement: Score 3 points(zero means bad, one means average and two means good).;Recovery time. Timepoint: End of study. Method of measurement: chronometer.
- Secondary Outcome Measures
Name Time Method