The prednisolone prescription effect on post CABG surgery inflammatory mediators

Phase 2

• Conditions: coronary artery disease.; Ischaemic heart diseases; I20-I25

• Registration Number: IRCT201010022622N2
• Lead Sponsor: Tehran Heart Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1- age over 18. 2- written informed consent. 3- patients who are candidate for open heart surgery.
Exclusion criteria: 1- recent use of systemic corticosteroid. 2- history of bacterial or fungal infection in the past two weeks. 3- history of sensitivity to corticosteroids. 4- uncontrolled diabetes mellitus. 5- history of renal failure 6- liver failure or elevated liver enzymes.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ength of stay in ICU and Intubation time. Timepoint: after transferring the patient to surgery ward. Method of measurement: questionnaire.

Secondary Outcome Measures

Name	Time	Method
Reduction of inflammatory mediators. Timepoint: before, 6 and 48 hours following operation. Method of measurement: Blood test.