Differentiate and assess the effectiveness of locally delivered 1.2% Rosuvastatin gel and tetracycline fibre as a treatment of Periodontitis.
Not Applicable
Completed
- Conditions
- Health Condition 1: K053- Chronic periodontitis
- Registration Number
- CTRI/2021/04/033057
- Lead Sponsor
- DR AASTHA DEBNATH
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 75
Inclusion Criteria
1)SYSTEMICALLY HEALTHY PARTICIPANTS DIAGNOSED WITH LOCALIZED OR GENERALIZED STAGE II/III PERIODONTITIS22 WITHIN THE AGE GROUP OF 30-60 YEARS.
2)PARTICIPANTS WITH AT LEAST THREE NONADJACENT SITES WITH 5-7 MM OF PROBING POCKET DEPTH (PPD) WITH NO CONTRAINDICATION TO PERIODONTAL THERAPY.
3)PARTICIPANTS SHOULD NOT HAVE RECEIVED ANY ANTIBIOTIC AND PERIODONTAL THERAPY FOR PAST 6 MONTHS
Exclusion Criteria
1)PATIENT WITH HABIT OF TOBACCO CHEWING AND SMOKING.
2)PARTICIPANTS WHO ARE PREGNANT AND LACTATING WOMEN
3)PATIENTS USING ANTI-MICROBIAL MOUTHWASH IN THE PAST 2 MONTHS
4)PARTICIPANTS WITH ALLERGY TO STATINS/TETRACYCLINE.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1)PLAQUE INDEX <br/ ><br>2)PROBING DEPTH 5MM <br/ ><br>3)RELATIVE ATTACHMENT LEVEL <br/ ><br>4)BLEEDING INDEX <br/ ><br>5)GINGIVAL MARGIN POSITION <br/ ><br>6)INTRABONY DEFECT <br/ ><br>Timepoint: AT BASELINE <br/ ><br>AT 3 MONTHS <br/ ><br>AT 6 MONTHS <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1)PLAQUE INDEX <br/ ><br>2)PROBING DEPTH 5MM <br/ ><br>3)RELATIVE ATTACHMENT LEVEL <br/ ><br>4)BLEEDING INDEX <br/ ><br>5)GINGIVAL MARGIN POSITION <br/ ><br>6)INTRABONY DEFECT <br/ ><br>Timepoint: BASLINE TO 6 MONTHS