Expressive Writing in Male Infertility

Not Applicable

Completed

• Conditions: Infertility, Male
• Interventions: Behavioral: Expressive writing

• Registration Number: NCT00385346
• Lead Sponsor: University Hospital, Bonn

Brief Summary

The purpose of this study is to determine whether expressive writing can be effective in improving the well-being and sperm quality in patients with male infertility.

Detailed Description

Expressive writing is a therapeutic intervention designed by the psychologist James W. Pennebaker. Individuals write on three days for about 20 minutes about particularly stressful experiences in their life. Several studies showed that expressive writing can have beneficial effects on the frequency of health care utilization and well-being. Particularly in patients with rheumatism, kidney cancer and posttraumatic stress disorder expressive writing showed an positive effect on subjective well-being. Furthermore, in several studies expressive writing showed a positive effect on immune parameters.

As many studies suggest an important negative effect of stress on well-being and sperm parameters in male infertility, we want to investigate the effect of expressive writing in male infertility.The expressive writing condition is compared to a non emotional writing condition, in which individuals write about mainly non emotional topics such as time management. In this randomized-controlled trial subjects were allocated sequentially by block wise randomization (block size of 4). For randomization a computer generated random list was used. The allocation was concealed in a series of numbered sealed envelopes. The envelope was opened immediately before the first writing session.

Study Timeline

• Study First Submitted: 2006-10-05
• Study First Submitted QC: 2006-10-05
• Study First Posted: 2006-10-09
• Study Start: 2006-11
• Primary Completion: 2008-06
• Study Completion: 2009-02
• Status Verified: 2009-09
• Last Update Submitted: 2010-06-29
• Last Update Posted: 2010-06-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 56

Inclusion Criteria

• Male infertile patients with a pathological spermiogram according to WHO criteria

Exclusion Criteria

• Drugs affecting sperm quality
• Patients with chromosomal anomalies affecting sperm quality (e.g. Klinefelter- Syndrome)
• Severe Psychiatric disorder defined as psychotic disorder (schizophrenia, bipolar disorder) or substance-related disorder
• Patients currently in psychotherapeutic or psychiatric therapy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
A 1	Expressive writing	Expressive writing

Primary Outcome Measures

Name	Time	Method
Scores on rating scale for perceived stress in infertility	3 months

Secondary Outcome Measures

Name	Time	Method
Sperm parameters	3-12 months
Scores on rating scale for personality dimensions	3 months
Score on rating scale for coping	3 months

Trial Locations

Locations (1)

University of Bonn, Department of Psychosomatic Medicine; 🇩🇪 Bonn, Germany