Acute Effects of Caffeinated and Decaffeinated Coffee on Bioelectrical Impedance Analysis

Not Applicable

Completed

• Conditions: Body Composition Measurement

• Registration Number: NCT06754748
• Lead Sponsor: Marmara University

Brief Summary

This study investigates how caffeinated coffee, decaffeinated coffee, and water affect body composition, as measured by BIA. Participants were divided into three groups, consuming their respective beverages, with measurements taken over a 120-minute period. The study aimed to determine if caffeine or fluid intake is the primary driver of changes in body composition parameters.

Detailed Description

This study aims to address these gaps by examining how caffeinated coffee, decaffeinated coffee, and water influence BIA measurements at multiple intervals post-consumption (baseline, 30, 60, 90, and 120 minutes). By incorporating a controlled study design with separate water-only and caffeine-free groups, this methodology overcomes the limitations of previous studies that lacked comprehensive control conditions. By determining whether caffeine or fluid volume primarily drives changes in BIA parameters and identifying the timing of these effects, this research seeks to improve the understanding of external factors affecting BIA, providing valuable insights for accurate body composition assessments.

Participants were divided into three groups based on their average daily caffeine consumption: caffeinated coffee, decaffeinated coffee, and water.

To standardize caffeine and fluid intake, filter coffee was chosen for its consistency in caffeine content and fluid volume. Both caffeinated and decaffeinated Arabic coffee were prepared using 11 g of coffee per 200 ml of water. The coffee was weighed using a precision balance and brewed with a filter coffee machine to ensure uniform preparation.

Participants were instructed to adhere to the following restrictions prior to the analysis day: a 12-hour fast, avoidance of excessive fluids, abstinence from caffeine-containing beverages, no showering or sauna use, no alcohol consumption for 48 hours, and no heavy exercise for 4-12 hours before the measurement. These restrictions minimized potential confounding effects on hydration or metabolic state, ensuring reliable BIA measurements.

The first BIA measurements were taken before any beverage consumption. Subsequently, participants consumed 200 ml of caffeinated coffee, decaffeinated coffee, or water, depending on their group. BIA measurements were repeated at 30, 60, 90, and 120 minutes post-consumption.

Study Timeline

• Study Start: 2023-02-25
• Primary Completion: 2023-03-25
• Study Completion: 2023-05-20
• Status Verified: 2024-12
• Study First Submitted: 2024-12-23
• Study First Submitted QC: 2024-12-23
• Last Update Submitted: 2024-12-23
• Study First Posted: 2025-01-01
• Last Update Posted: 2025-01-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 28

Inclusion Criteria

• Healthy adults aged ≥18 years.
• BMI between 18.5 and 29.9 kg/m².
• Regular coffee consumers.
• Participants providing written informed consent.

Exclusion Criteria

• Individuals on medication or hormone therapy within the last 6 months.
• Medical conditions affecting caffeine metabolism (e.g., allergies or intolerances).
• Chronic or acute diseases.
• Significant appetite or eating disturbances in the past 6 months.
• Participants menstruating on the day of analysis.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Change in Body Fat Mass	Baseline, 30, 60, 90 and 120 minutes	BIA measurements were recorded for the body fat mass (kg) at baseline, 30, 60, 90, and 120 minutes.
Change in body fat percentage	Baseline and 30, 60, 90, and 120 minutes.	BIA measurements were recorded for the body fat percentage (%) at baseline, 30, 60, 90, and 120 minutes.
Change in fat-free mass	Baseline and 30, 60, 90, and 120 minutes.	BIA measurements were recorded for the fat-free mass (kg) at baseline, 30, 60, 90, and 120 minutes.
Change in muscle mass	Baseline and 30, 60, 90, and 120 minutes.	BIA measurements were recorded for the muscle mass (kg) at baseline, 30, 60, 90, and 120 minutes.
Change in total body water	Baseline and 30, 60, 90, and 120 minutes.	BIA measurements were recorded for the total body water (kg) at baseline, 30, 60, 90, and 120 minutes.

Secondary Outcome Measures

Name	Time	Method
Change in Body Weight	Baseline, 30, 60, 90 and 120 minutes	Body weight (kg) was measured with BIA at baseline, 30, 60, 90 and 120 minutes and recorded.
Change in Body Mass Index	Baseline, 30, 60, 90 and 120 minutes	Body mass index was calculated from weight and height and presented as kg/m² at baseline, 30, 60, 90 and 120 minutes and recorded.

Trial Locations

Locations (1)

Marmara University, Faculty of Health Sciences; 🇹🇷 Istanbul, Maltepe, Turkey