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Clinical Trials/NCT04018443
NCT04018443
Unknown
Not Applicable

The Relation Between Common Carotid Artery Diameter and Central Venous Pressure for Assessment of Intravascular Fluid Status After Major Surgeries: An Observational Study

Beni-Suef University1 site in 1 country60 target enrollmentApril 7, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Fluid Resuscitation Monitoring Non-invasively
Sponsor
Beni-Suef University
Enrollment
60
Locations
1
Primary Endpoint
Common Carotid Artery diameter at expiration (millimetre)
Last Updated
6 years ago

Overview

Brief Summary

Recently, bedside ultrasound has become an important tool for the simple and non-invasive hemodynamic assessment of critically ill patients. This applies not only to echocardiography but also to ultrasound of large extra-thoracic veins. The sonography can provide real time assessment of the vascular system and hemodynamic status at the bedside.

To our knowledge, there is one report about the association between sonographically assessed carotid artery diameter and intravascular volume, which raised recommendation for further studies including the interplay between carotid geometry and intravascular fluid status.

Aim of the study:

The aim of this work is to evaluate the accuracy of noninvasive techniques for assessment of intravascular volume status by Sonographic assessment of both the common carotid artery diameter (CCA) and the central venous pressure (CVP) in response to a bolus of crystalloid solution infusion and to find the correlation between CCA diameter and CVP as the primary outcome in adults patients after major surgeries who needs close assessment and maintenance of the intravascular volume status.

Registry
clinicaltrials.gov
Start Date
April 7, 2019
End Date
October 7, 2019
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Samaa A. Kasem

Associate professor

Beni-Suef University

Eligibility Criteria

Inclusion Criteria

  • Male and female patients (age 20-60 years).
  • ASA physical status I and II
  • Patients who are able to breathe spontaneously and lie supine.
  • Patients who have CVP catheter (subclavian or internal jugular vein).

Exclusion Criteria

  • History of carotid artery surgery
  • Significant cardiac disease (cardiomyopathy and/or moderate to severe valvular heart lesion).
  • Significant hepatic disease (Child-Pugh score B or C ).
  • Renal failure.
  • Obesity: BMI ˃ 30 kg/m2
  • Need for mechanical ventilation.
  • Unstable vital signs during the process of sonography (e.g. the patients on vasoactive drugs)

Outcomes

Primary Outcomes

Common Carotid Artery diameter at expiration (millimetre)

Time Frame: 5 minutesafter fluid bolus infusion

common carotid artery internal diameter changes songraphically measured to assess intravenous resuscitation

Central venous pressure (centimetre water)

Time Frame: 5 minutes after fluid bolus infusion

Central venous pressure changes measured to assess intravenous resuscitation

Study Sites (1)

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