Endometrial Advancement After Rec or u-HCG Triggering
Phase 4
Completed
- Conditions
- Infertility
- Interventions
- Drug: 10000 IU urinary HCGDrug: 250 mcg recombinant HCG
- Registration Number
- NCT00953628
- Lead Sponsor
- Universitair Ziekenhuis Brussel
- Brief Summary
The purpose of this study is to investigate any potential advantages of replacing human chorionic gonadotropin (uhCG) with recombinant human chorionic gonadotropin (recHCG) for final oocyte maturation with regard to Ovarian hyperstimulation syndrome (OHSS)pathophysiology, endometrium receptivity and embryo quality and clinical pregnancy.
- Detailed Description
Biopsies of endometrium were taken in different groups Pregnancy rates were compared among defferent groups
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 130
Inclusion Criteria
- Less than 36 years old
- Male or tubal infertility
- FSH<12 on day 3
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Exclusion Criteria
- Endometriosis stage 3 & 4
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description o Group A=uHCG ovul trig 10000 IU urinary HCG HCG for triggering o Group B=recHCG ovul trig 250 mcg recombinant HCG recombinant HCG for triggering
- Primary Outcome Measures
Name Time Method endometrium histology on the day of OPU day of oocytre pick up
- Secondary Outcome Measures
Name Time Method pregnancy rate 14 days after oocyte pick up
Trial Locations
- Locations (1)
Centre for Reproductive Medicine, UZ Brussel
🇧🇪Brussels, Jette, Belgium