Comparative Evaluation of Resistin levels in Gingival Crevicular Fluid and Saliva of Patients with Hypertension and Periodontitis

Not Applicable

Not yet recruiting

Conditions: Health Condition 1: K053- Chronic periodontitisHealth Condition 2: I159- Secondary hypertension, unspecified

Registration Number: CTRI/2022/05/042673

Lead Sponsor: DR VARSHA URLAM

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: Not specified

Target Recruitment: 80

Inclusion Criteria

Inclusion Criteria:

a) Patients who are 18 years and above who are willing to participate.

b) Presence of at least 20 natural teeth excluding third molars.

c) Chronic periodontitis as stated by American Academy of Periodontology (AAP) classification 2018: presence of > 2 teeth in each quadrant with a PPD of > 5mm, CAL of > 4mm and radiographic evidence of interproximal bone loss. Along with BOP at >50% of sites of full mouth.

d) Patients who are hypertensive as per Blood pressure classification as given by American Heart Association 2017 guidelines for prevention, detection, evaluation and management of High Blood Pressure in adults.

Exclusion Criteria

a) Patients with any other known systemic disorder.

b) Patients who have received any form of periodontal therapy, surgical or non-surgical within past 6 months.

c) Patients who have received any antibiotic or anti-inflammatory drug regimen within past 6 months.

d) Patients who smoke or chew any form of tobacco.

e) Patients who are pregnant or lactating.

f) Patients who are undergoing any orthodontic treatment.

g) Physically and mentally challenged patients.

h) Patients prone to or with a history of allergic reactions to any component of the investigating materials.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.To comparatively evaluate Resistin levels in GCF and saliva of patients with Hypertension and Chronic Periodontitis. <br/ ><br>2.To assess and evaluate the role of Resistin as a diagnostic biomarker in patients of Hypertension and Chronic Periodontitis. <br/ ><br>Timepoint: 1 DAY

Secondary Outcome Measures