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Comparision of clinical efficacy of Intravenous acetaminophen vs ketorolac to relieve pain in renal colic

Phase 2
Conditions
Acute Renal Colic.
Urinary calculus, unspecified
Registration Number
IRCT2015090223855N1
Lead Sponsor
Vice- Chancellor for Research, Semnan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
120
Inclusion Criteria

Patients will eligible for inclusion with a history of unilateral abdominal or flank pain that the treating emergency physicians suspect to be renal colic, with ultrasonography or CT Scan or intravenous pyelography (IVP) findings consistent with the diagnosis of renal colic or passage of the calculus.
Only patients displaying at least a visual analog
scale (VAS) =30/100 will include. Patients can not be
include if they have a history of peptic ulcer disease, asthma, bleeding disorder (including the use of oral anticoagulant), impaired renal or hepatic function, suspected hypersensivity to aspirin or NSAID or paracetamol, and if they are pregnant and breast-feeding women. Patients can not be include if they have received painkillers within 6 hours before presentation and if they are younger than 18 and greater than 55 years old.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
evel of pain. Timepoint: before treatment initiation and sequentially at 20,40,60 minutes. Method of measurement: Visual Analogue Scale.
Secondary Outcome Measures
NameTimeMethod
Heart Rate. Timepoint: before treatment initiation and sequentially at 20,40,60 minutes. Method of measurement: Radial Pulse.;Blood pressure. Timepoint: before treatment initiation and sequentially at 20,40,60 minutes. Method of measurement: sphygmomanometer.;Body temprature. Timepoint: before treatment initiation and sequentially at 20,40,60 minutes. Method of measurement: Thermometer(axillary).;Respiratory rate. Timepoint: before treatment initiation and sequentially at 20,40,60 minutes. Method of measurement: Physical examination.;Size of renal calculi. Timepoint: after pain relief. Method of measurement: imaging findings.;Location of renal calculi. Timepoint: after pain relief. Method of measurement: imaging findings.;Paracetamol side effects. Timepoint: in all the time in care. Method of measurement: questionnaire and physical examination.;Ketorolac side effects. Timepoint: in all the time in care. Method of measurement: questionnaire and physical examination.
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