Perioperative Nutritional and Hemodinamic Support in Retroperitoneal Sarcoma Patients. A Phase II Prospective Feasibility Study.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 35
- 主要终点
- Rate of Adherence to protocol
研究概览
简要总结
Prospective feasibility study of perioperative nutrition in patients affected by primary retroperitoneal sarcoma
详细描述
Aim of our study was to investigate the feasibility of a prehabilitation policy to optimize protein energetic reserves in a group of patients affected by primary localized RPS, candidate to a multiple organ resection surgery, as well as the feasibility of a standardized nutritional postoperative caloric target and its adequacy.
研究设计
- 研究类型
- Interventional
- 干预模型
- Sequential
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •every patient with retroperitoneal sarcoma scheduled for surgery
排除标准
- •chronic renal failure
- •diabetes mellitus
- •emergency surgery
- •physical status classification system ASA>3
- •any contraindication to arterial catheter in Femoral artery for PICCO hemodynamic monitoring
研究组 & 干预措施
Primary retroperitoneal sarcoma
All eligible patients are screened in preoperative phase, at least 30 days before surgery, for presence of protein energetic malnutrition (PEM). PEM is defined according to biochemical and physiological parameters (Table). 3 class of PEM are identified: no PEM, mild PEM and serious PEM. Different nutritional oral supplements are provided according to the degree of malnutrition.
干预措施: Oral Nutritional Support (Dietary Supplement)
结局指标
主要结局
Rate of Adherence to protocol
时间窗: 15 days
Rate of adherence to prescribed oral nutritional support
次要结局
未报告次要终点