Comparative Evaluation of Efficacy of Herbal Mouthwash (Oralife) with Chlorhexidine Mouthwash (Rexidine SRS) in Generalized Chronic Periodontitis Patients- A Randomized Clinical Trial
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 62
- 试验地点
- 1
- 主要终点
- 1. Plaque Index (P.I.) (Silness and Loe, 1964)
研究概览
简要总结
Aim-To clinically compare and evaluate the efficacy of herbal mouthwash (OralifeTM) with Chlorhexidine Mouthwash(Rexidine® SRS).
Materials and Methods-
This study is an Interventional Prospective Clinical Trial. It is a double-blinded, single-centre, Institution-based study. The patients selected as per the inclusion and exclusion criteria, will be randomly allotted by a computerized automated randomization method into 2 groups, Group A and Group B, and treated as follow.
Group A: Scaling and chlorhexidine (Rexidine® SRS 0.2%) mouthwash
Group B: Scaling and herbal (OralifeTM) mouthwash
The following clinical parameters will be recorded at baseline (post scaling), 1 month post-scaling.
- Plaque Index (P.I.) (Silness and Loe, 1964)
- Gingival Index (G.I.) (Loe and Silness, 1963)
- Probing Pocket Depth (PPD)
- Clinical Attachment Loss(CAL)
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients in the age group between 20-60 yrs.
- •2.Patients diagnosed with Chronic Periodontitis.
- •3.Patients who are non smokers or do not consume tobacco in any other form.
- •4.Patients with good systemic health.
排除标准
- •1.Individuals suffering from any systemic diseases.
- •Individuals wearing fixed or removable orthodontic appliances or prosthesis
- •Pregnant and lactating females
- •Individuals taking medications since prolonged duration 5.
结局指标
主要结局
1. Plaque Index (P.I.) (Silness and Loe, 1964)
时间窗: Baseline, 1 month Post treatment
2. Gingival Index (G.I.) (Loe and Silness, 1963)
时间窗: Baseline, 1 month Post treatment
3. Probing Pocket Depth (PPD)
时间窗: Baseline, 1 month Post treatment
次要结局
- Clinical attachment level(Baseline, 1 month post treatment)
研究者
Dr Aishwary Patil
Nair Hospital Dental College