Splenectomy During Whole Liver Transplantation
Completed
- Conditions
- End Stage Liver Disease
- Interventions
- Procedure: Splenectomy
- Registration Number
- NCT03609411
- Lead Sponsor
- Hospices Civils de Lyon
- Brief Summary
Indications for splenectomy during whole liver transplantation remain controversial and splenectomy is often avoided because of common complications. The objective is to evaluate specific complications of these combined procedures.
- Detailed Description
Data on patients who underwent splenectomy during liver transplantation were retrospectively analyzed . Participants underwent splenectomy as part of routine medical care. Patients undergoing simultaneous liver transplantation and splenectomy were matched to a non-splenectomy group.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 141
Inclusion Criteria
- Patients undergoing liver transplantation between 1994 and 2013
Exclusion Criteria
- Data from living donor patients, split liver transplantation, patients with pre- or post-operative splenectomy in medical history, and patients under 16 years were excluded from analysis
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Splenectomy Splenectomy Patients undergoing liver transplantation with simultaneous splenectomy
- Primary Outcome Measures
Name Time Method 3-month post-operative mortality At 3 months post surgery
- Secondary Outcome Measures
Name Time Method Mortality at 5 years Five years after surgery Post-operative morbidity 3 months post surgery Incidence of portal-vein thrombosis within 3 months post liver transplantation
One-year mortality One year after surgery
Trial Locations
- Locations (1)
Hopital de la Croix-Rousse
🇫🇷Lyon, France