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A Clinical Study of Remimazolam Tosilate Compared to Propofol for General Anesthesia During Elective Surgery

Phase 3
Completed
Conditions
Anesthesia for Elective Surgery Patients
Interventions
Registration Number
NCT03921775
Lead Sponsor
Jiangsu HengRui Medicine Co., Ltd.
Brief Summary

The study is being conducted to evaluate the efficacy and safety of remimazolam tosilate compared to propofol for general anesthesia during elective surgery.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
330
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Treatment group ARemimazolam TosilateIV pumping of remimazolam tosilate at 6mg/kg/h for anesthesia induction and 1mg/kg/h for anesthesia maintenance
Treatment BPropofolIV pumping of propofol at 120\~150mg/kg/h for anesthesia induction and 3\~12mg/kg/h for anesthesia maintenance
Primary Outcome Measures
NameTimeMethod
Percentage(%) of paticipants who experienced successful anesthesia during operation in each groupAverage of 2 hours
Secondary Outcome Measures
NameTimeMethod
Time from stop of investigational medicinal product to MOAA/S Score=5Average of 2 hours
Time from start of investigational medicinal product administration to loss of consciousnessAverage of 2 hours
Time from stop of investigational medicinal product to Aldrete Score>9Average of 2 hours

Trial Locations

Locations (1)

Peking Union Medical College Hospital

🇨🇳

Beijing, Beijing, China

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