Effects of resistance training and nutritional support on osteosarcopenia in older, community-dwelling postmenopausal Korean females
- Conditions
- Not Applicable
- Registration Number
- KCT0008291
- Lead Sponsor
- Chungnam National University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 34
1. Post-menopausal female aged between 65 years and 90 years
2. Diagnosed with sarcopenia
3. Diagnosed with osteopenia or osteoporosis
1. secondary osteoporosis
2. regularly taking medications that can affect the bone or muscle more than a month before the study (e.g., anticonvulsants, steroids)
3. a diagnosis of diabetes mellitus, thyroid disease, parathyroid disease, or Paget’s disease of bone
4. active malignancy requiring treatment
5. having implants, hardware, devices, or foreign material in the measurement area
6. chronic kidney disease more severe than stage 3 (GFR<60 ml/min)
7. alcohol addiction
8. a history of previous fragile fractures (radius, hip, or spine)
9. inability to understand or to participate in the study protocol
10. refusal to participate.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The patient's appendicular muscle mass, skeletal muscle index, and bone mineral density (measurement site - spine, femur neck) measured through DEXA scan
- Secondary Outcome Measures
Name Time Method Appendicular muscle mass, whole-body phase angle, lean body mass, total fat mass (%) and skeletal muscle index measured by bioelectrical impedance analysis, patient's quality of life and psychological state, patient's functional evaluation, muscle quality, and CTX