Comparison of the effect on post-operative pain, patient satisfaction and the incidence of chronic pain by the use of either a transversus abdominis plane nerve block or a standard regime with morphine in patients undergoing surgery for total abdominal hysterectomy

Completed

• Conditions: Total abdominal hysterectomy; Surgery; Hysterectomy

• Registration Number: ISRCTN69387981
• Lead Sponsor: Belfast Health and Social Care Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-10-14
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

1. American Society of Anaesthesiologists (ASA) class I - III
2. Patients able to give written informed consent
3. Patients requiring total abdominal hysterectomy
4. Female patients aged 18 years and over

Exclusion Criteria

1. Patients requiring total abdominal hysterectomy secondary to neoplasia
2. History of allergy to any of the medications used in the study
3. Pre-operative use of opiates
4. Patients unable to use patient controlled analgesia system

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The reduction in visual analogue scores (VAS) in the post-operative period for patients undergoing total abdominal hysterectomy.

Secondary Outcome Measures

Name	Time	Method
1. Usage of morphine sulphate in the post-operative period<br>2. Incidence of nausea and/or vomiting within the first 48 hours after surgery<br>3. Measurement of oxygen saturations without supplemental oxygen in both groups in the post-operative period<br>4. Incidence of complications associated with the analgesia techniques in both groups<br>5. Patient satisfaction with analgesia technique<br>6. Incidence of chronic pelvic pain at 3 months