The efficacy of dexamethasone for pemetrexed-induced rash preventio

Not Applicable

• Conditions: non-small cell lung cancer, malignant pleural mesothelioma

• Registration Number: JPRN-UMIN000025666
• Lead Sponsor: Department of Respiratory medicine and Rheumatology, Tokushima University Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-04-01
• Study Completion: 2019-04-22
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

Not provided

Exclusion Criteria

1)Patients with contraindication of dexamethasone or pemetrexed 2)Using systemic corticosteroid 3)Patients with active infection 4)Using anti-allergenic drug 5)Patients with severe diabetes mellitus that corticosteroids administration is unacceptable 6)Patients with active for hepatitis B antigen and anti-hepatitis C antibody 7)Pregnant / lactating woman, a woman with an intention of pregnancy, a man with a partner who has an intention of pregnancy 8)Combination with cisplatin 9)Patients are judged unqualified for this study by attending physician

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of rash within 21 days of pemetrexed administration