A Randomized Clinical Trial Comparing Computer-assisted Cognitive Rehabilitation (CACR), Psycho-stimulants, and Placebo CACR in the Treatment of Attention Deficit/ Hyperactivity Disorder
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 34
- 试验地点
- 1
- 主要终点
- Forward/Reversed digit span tasks from the WISC-R testing battery.
研究概览
简要总结
Current research aimed to compare the efficacy of computer-assisted cognitive rehabilitation (CACR), stimulant drugs and Placebo CACR on executive functions and clinical symptoms of children with attention deficit/hyperactivity disorder (ADHD).
详细描述
The investigators administered a randomized controlled trial (RCT) through random assignment of ADHD subjects in to three different groups to compare the effects of CACR, immediate-release methylphenidate, and a Placebo CACR (i.e. some computerized tasks assumed not having any therapeutic effects) on the functioning of children with ADHD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 7 Years 至 12 Years（Child）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •ADHD diagnosis
- •age between 7 and 12
排除标准
- •sever co-morbid disorder
- •disability
- •sever medical condition
研究组 & 干预措施
Computerized cognitive rehabilitation
-Computer-assisted cognitive rehabilitation (CACR): 20 Ninety-minute sessions of CACR.
干预措施: Computerized cognitive rehabilitation (Other)
Placebo CACR [PCACR]
-PCACR group simultaneously received 20 Ninety-minute sessions of Placebo CACR.
干预措施: Placebo CACR [PCACR] (Other)
Ritalin
-2 to 3 doses of 10 mg Ritalin tablets per day during two months.
干预措施: Ritalin (Drug)
结局指标
主要结局
Forward/Reversed digit span tasks from the WISC-R testing battery.
时间窗: 5 months
Reversed digit span from the WISC-R (Wechsler, 1974) was used to measure executive verbal WM and the forward digit span was used to measure short-term memory.
Raven's colored progressive matrices.
时间窗: 5 months
Raven's colored progressive matrices (Raven, 1995) was used to measure complex non-verbal reasoning.
Persian software for the continuous performance test [CPT]
时间窗: 5 months
The Persian software of CPT is a visual CPT test.
Persian software for the Tower of London Test [TOL]
时间窗: 5 months
Persian TOL is a software version of tower of London test (TOL) which was developed in Iran.
Span board task from the Lumosity.com online software (Lumosity.com, 2012)
时间窗: 5 months
SNAP-IV scales
时间窗: 5 months
次要结局
未报告次要终点