A study on the classification of inflammatory bowel disease by the patterns of immunological profiles
Not Applicable
- Conditions
- Crohn's Disease, ulcerative colitis
- Registration Number
- JPRN-UMIN000011113
- Lead Sponsor
- Kobe University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Not provided
Exclusion Criteria
[Patients] Pregnant women are excluded. Patients who have obvious intestinal disease and/or systemic inflammation caused by other than inflammatory bowel disease, such as advanced cancer, systemic autoimmune disease, and infections are excluded. Patients with bleeding tendency are excluded. [Healthy volunteers] Pregnant women are excluded. Persons with bleeding tendency are excluded.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The immunological profiling will be determined by the measurement of cytokines, chemokines and other factors in the serum and intestinal tissue samples. The patients will be classified into subgroups by the immunological features, and the correlation of endoscopical disease activity, clinical course, and the responsiveness and/or resistance to therapy protocol with those subgroups will be analyzed.
- Secondary Outcome Measures
Name Time Method The feasibility of immunological profiling for the selection of proper therapeutic strategy and prediction of the clinical course.