Impact of serum progesterone level on the ART cycle.

Not Applicable

Completed

• Conditions: Health Condition 1: O090- Supervision of pregnancy with history of infertility

• Registration Number: CTRI/2022/11/046995
• Lead Sponsor: Indira IVF Hospital Pvt Ltd

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2023-09-18
• Last Update Posted: 13 November 2023

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 358

Inclusion Criteria

1. Patients who signed the written informed consent document.

2. 21-40 years old females (both inclusive).

3. Having two or more implantation failures after good embryo transfer (Gardener’s grade 3/4/5/AA/AB/BA/BB).

4. Patients undergoing their IVF/ICSI cycle with single embryo transfer (SET) or double embryo transfer (DET) of frozen blastocyst stage embryos (day 5/6) on an HRT cycle.

5. BMI: 18.5 - 30.0 kg/m2 (both inclusive).

6. Negative serological tests for HIV, HBV, HCV, RPR.

Exclusion Criteria

1. Uncontrolled diabetes, hypertension, heart disease and with known case of autoimmune disease.

2. Male partner with total sperm count less than 5 million per ml.

3. Surgically retrieved sperm for ICSI .

4. Adenomyosis

5. Endometrial thickness less than 7mm on day of embryo transfer.

6. Removal of myomas greater than 4 cm, within two months prior to embryo transfer.

7. Salpingectomy or tubal clipping for hydrosalpinx within one month prior to embryo transfer.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical pregnancy rateTimepoint: 4th week after Embryo Transfer

Secondary Outcome Measures

Name	Time	Method
Implantation rateTimepoint: 4 wks following Embryo Transfer;Live Birth RateTimepoint: more than 20 weeks after Embryo Transfer;Miscarriage RateTimepoint: Within 20 weeks of Embryo Transfer;Ongoing Pregnancy rateTimepoint: 10 week after Embryo transfer