REMOTE ISCHEMIC CONDITIONING OR ACUTE ISCHEMIC STROKE-Study Protocol for a Randomized Controlled Trial
Not Applicable
- Conditions
- ischemic stroke
- Registration Number
- JPRN-UMIN000044566
- Lead Sponsor
- Tokyo Women's Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
Not provided
Exclusion Criteria
1 mRS is more than 2 before stroke onset 2 rt-PA and/or EVT treated AIS after registration 3 Within 12 hours after rt-PA administration or EVT 4 History of PAD 5 Systric blood pressure is more than 180 mmHg 6 Patients deemed unsuitable as subjects by the investigator
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method good functional outcome at 3-months after stroke onset, assessed by the mRS, with a target mRS score of 0-1 in the mild group, 0-2 in the moderate group, and 0-3 in the severe group.
- Secondary Outcome Measures
Name Time Method 1) the proportion of patients with a good functional outcome (assessed by the mRS) in each group at 3 months after stroke onset; 2) the change in NIHSS scores from before RIC to after RIC; 3) the incidence of major adverse cardiovascular events, aspiration pneumonia, and all-cause mortality after stroke onset; 4) the frequency of adverse RIC-related events; and 5) the proportion of patients with a mRS score of 0-1.