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Do motor abnormalities of esophageal muscle in achalasia patients explain non cardiac chest pain episodes?

Withdrawn
Conditions
chest pain in patients with failure of the esophageal muscle to relax
10017977
Registration Number
NL-OMON29962
Lead Sponsor
niversitair Medisch Centrum Utrecht
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Withdrawn
Sex
Not specified
Target Recruitment
20
Inclusion Criteria

achalasia patients with chest pain episodes at least 5 times a week

Exclusion Criteria

Lower esophageal sphincter pressure > 10 mmHg
clinical heart disease
requirements of (anti)cholinergic drugs or beta-adrenergic blocking agents
alcohol and/or drug abuse
pregnancy

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>During each chest pain event, manometric contraction types will be described.<br /><br>pH-metry and impedance will be used to describe acid reflux events respectively<br /><br>stasis of fluids in the esophagus during chest pain events. </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>none</p><br>
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