EARLY WITHDRAWAL FROM MECHANICAL VENTILATIONUSING NEW DEVICE IN COMPARISON TO STANDARD STRATEGY INHYPOXEMIC RESPIRATORY FAILURE
Not Applicable
Completed
- Conditions
- Health Condition 1: J969- Respiratory failure, unspecified
- Registration Number
- CTRI/2021/07/034659
- Lead Sponsor
- none
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
All adult pts (age above 18yrs) who will receive invasive mechanical ventilation through endotracheal tube for more than 48hrs for hypoxemic respiratory failure
Exclusion Criteria
•Age less than 18yrs
•Type 2 respiratory failure
•Tracheostomized patients
•Profound neurological deficit and altered sensorium
•Contraindication to HFNC application (base of skull fracture, known nasal obstruction and nasal trauma)
•Psychiatric, agitated or non-cooperative patients
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare weaning failure (defined by need of reintubation within 48hrs of extubation) in both groupsTimepoint: To compare weaning failure (defined by need of reintubation within 48hrs of extubation) in both groups
- Secondary Outcome Measures
Name Time Method to compare the days of sedation requirement and all-cause mortalityTimepoint: during icu stay;To compare the ICU length of stayTimepoint: during icu stay;To compare the incidence of ventilator associated pneumonia (VAP)Timepoint: during icu stay;to compare the invasive ventilation free daysTimepoint: during icu stay;To compare total ventilation daysTimepoint: during icu stay