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Molecular Diagnostic Platform for AML

Conditions
Acute Myeloid Leukemia (AML)
First Posted Date
2020-06-25
Last Posted Date
2021-09-05
Lead Sponsor
PETHEMA Foundation
Target Recruit Count
2000
Registration Number
NCT04446741
Locations
🇪🇸

Hospital Universitario Reina Sofía, Córdoba, Spain

🇪🇸

Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas De Gran Canaria, Spain

🇪🇸

Hospital Doce de Octubre, Madrid, Spain

and more 4 locations

A Safety and Efficacy Study of SHR-1702 Monotherapy in Patients With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Phase 1
Completed
Conditions
AML
MDS
Interventions
First Posted Date
2020-06-23
Last Posted Date
2023-08-24
Lead Sponsor
Jiangsu HengRui Medicine Co., Ltd.
Target Recruit Count
31
Registration Number
NCT04443751
Locations
🇨🇳

Blood disease hospital of Chinese Academy of Medical Sciences, Tianjin, Tianjin, China

JSP191 Antibody Conditioning Regimen in MDS/AML Subjects Undergoing Allogenic Hematopoietic Stem Cell Transplantation

Phase 1
Conditions
MYELODYSPLASTIC SYNDROME; MDS
ACUTE MYELOID LEUKEMIA; AML
First Posted Date
2020-06-12
Last Posted Date
2021-06-11
Lead Sponsor
Jasper Therapeutics, Inc.
Target Recruit Count
40
Registration Number
NCT04429191
Locations
🇺🇸

City of Hope Comprehensive Cancer Center, Duarte, California, United States

🇺🇸

Stanford University, Stanford, California, United States

🇺🇸

Rush University Medical Center, Chicago, Illinois, United States

and more 3 locations

Combination of Donafenib and Cytarabine/Daunorubicin in Relapsed AML

Phase 1
Terminated
Conditions
Acute Myeloid Leukemia (AML)
Interventions
First Posted Date
2020-05-27
Last Posted Date
2022-12-01
Lead Sponsor
Suzhou Zelgen Biopharmaceuticals Co.,Ltd
Target Recruit Count
8
Registration Number
NCT04402723
Locations
🇨🇳

Institute of Hematology and Blood Disease Hospital, Tianjin, Tianjin, China

Haplo-identical Natural Killer (NK) Cells to Prevent Post-Transplant Relapse in AML and MDS (NK-REALM)

Phase 2
Withdrawn
Conditions
Myelodysplastic Syndromes (MDS)
Acute Myeloid Leukemia (AML)
First Posted Date
2020-05-20
Last Posted Date
2021-06-22
Lead Sponsor
Kiadis Pharma
Registration Number
NCT04395092
Locations
🇺🇸

Northside Hospital, Atlanta, Georgia, United States

🇺🇸

MD Anderson, Houston, Texas, United States

Decitabine+Cladribine+Cytarabine+Granulocyte Colony-stimulating Factor (D-CLAG) for Relapsed or Refractory Acute Myeloid Leukemia (AML)

Not Applicable
Conditions
Acute Myeloid Leukemia
First Posted Date
2020-05-04
Last Posted Date
2020-09-16
Lead Sponsor
Zhejiang University
Target Recruit Count
65
Registration Number
NCT04373395
Locations
🇨🇳

the First Affiliated Hospital,School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China

Comparing Post-Transplant Cyclophosphamide As GVHD Prophylaxis to Standard of Care for Acute Leukemia Patients

Phase 3
Recruiting
Conditions
Acute Lymphoblastic Leukemia (ALL) in Complete Remission
Acute Myeloid Leukemia (AML) in Remission
Interventions
First Posted Date
2020-03-19
Last Posted Date
2025-03-13
Lead Sponsor
King Faisal Specialist Hospital & Research Center
Target Recruit Count
264
Registration Number
NCT04314219
Locations
🇸🇦

King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia

Antigen-specific T Cell Therapy for AML or MDS Patients With Relapsed Disease After Allo-HCT

Phase 1
Active, not recruiting
Conditions
Acute Myeloid Leukemia (AML)
Myelodysplastic Syndrome (MDS)
First Posted Date
2020-02-25
Last Posted Date
2024-01-16
Lead Sponsor
NexImmune Inc.
Target Recruit Count
22
Registration Number
NCT04284228
Locations
🇺🇸

City of Hope Comprehensive Cancer Center, Duarte, California, United States

🇺🇸

Advent Health Medical Group Blood & Marrow Transplant, Orlando, Florida, United States

🇺🇸

Karmanos Cancer Institute, Detroit, Michigan, United States

and more 2 locations

A Phase Ib Study of APG-115 Single Agent or in Combination With Azacitidine or Cytarabine in Patients With AML and MDS.

Phase 1
Recruiting
Conditions
Acute Myeloid Leukemia (AML)
Myelodysplastic Syndromes (MDS)
Interventions
First Posted Date
2020-02-19
Last Posted Date
2024-10-11
Lead Sponsor
Ascentage Pharma Group Inc.
Target Recruit Count
102
Registration Number
NCT04275518
Locations
🇨🇳

The First Hospital of Peking University, Beijing, Beijing, China

🇨🇳

Guangzhou panyu central hospital, Guangzhou, Guangdong, China

🇨🇳

Nanfang Hospital of Southern Medical University, Guangzhou, Guangdong, China

and more 11 locations

A Study to Determine Safety, Tolerability, Pharmacokinetics, and Recommended Phase 2 Dose (RP2D) of Intravenous ABBV-184 in Adult Participants With Previously Treated Cancers

Phase 1
Terminated
Conditions
Non Small Cell Lung Cancer
Cancer
Acute Myeloid Leukemia (AML)
Interventions
First Posted Date
2020-02-17
Last Posted Date
2022-09-08
Lead Sponsor
AbbVie
Target Recruit Count
14
Registration Number
NCT04272203
Locations
🇺🇸

Fort Wayne Medical Oncology and Hematology, Inc /ID# 224332, Fort Wayne, Indiana, United States

🇺🇸

Gabrail Cancer Center Research /ID# 215667, Canton, Ohio, United States

🇺🇸

Thomas Jefferson University /ID# 218403, Philadelphia, Pennsylvania, United States

and more 14 locations

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