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Found 452 clinical trials|View Analysis

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Imapct of bioMarkers on Pharmacodynamics and Bleeding Risk of Direct Oral AntiCoagulants and Ticagrelor Study II

Not yet recruiting

Conditions: NOACs
Pharmacodynamics
Rivaroxaban
RNA Profile
Bleeding
Apixaban
Dabigatran
Pharmacogenomics
Novel Oral Anticoagulants
Edoxaban

Interventions: Genetic: Detection of genotype and RNA profile in platelet and white blood cell
Other: Indicators test related to platelet function
Other: Indicators test related to coagulation function

First Posted Date: 2023-03-10

Last Posted Date: 2023-03-10

Lead Sponsor: Peking University First Hospital

Target Recruit Count: 2000

Registration Number: NCT05764356

Locations: 🇨🇳
Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, China
🇨🇳
Anhui Provincial Hospital#The First Affiliated Hospital Of USTC#, Hefei, Anhui, China
🇨🇳
The Second Affiliated Hospital Of Chongqing Medical University, Chongqing, Chongqing, China

and more 3 locations

Effect on Markers of Cardiovascular, Reproductive and Cancer Risk From Firefighting Training

Not Applicable

Recruiting

Conditions: Micro RNA
Heat Stress
Heart Rate Variability
Reactive Hyperemia
DNA Strand Breaks
Oxidative Stress

Interventions: Other: Firefighting training exercises with no fire
Other: Firefighting training exercises under wood fire
Other: Firefighting training exercises under gas fire

First Posted Date: 2023-03-03

Last Posted Date: 2023-08-08

Lead Sponsor: National Research Centre for the Working Environment, Denmark

Target Recruit Count: 35

Registration Number: NCT05753254

Locations: 🇩🇰
The National Research Centre for the Working Environment, Copenhagen, Denmark
🇩🇰
Maria Helena Guerra Andersen, København Ø, Denmark

ORganoid GeneratioN Study for Cancer

Recruiting

Conditions: Cancer

Interventions: Genetic: DNA sequencing, RNA gene expression analysis, molecular profiling

First Posted Date: 2023-02-21

Last Posted Date: 2024-08-09

Lead Sponsor: Royal Marsden NHS Foundation Trust

Target Recruit Count: 100

Registration Number: NCT05734963

Locations: 🇬🇧
The Royal Marsden Hospital, London, United Kingdom

Study for Efficacy and Safety Assessment of the Drug RADAMIN®VIRO for COVID-19 Postexposure Prophylaxis

Phase 3

Completed

Conditions: COVID-19

Interventions: Drug: Placebo
Drug: Double-Stranded RNA sodium salt

First Posted Date: 2023-02-10

Last Posted Date: 2023-02-16

Lead Sponsor: Promomed, LLC

Target Recruit Count: 800

Registration Number: NCT05722691

Locations: 🇷🇺
Federal State Budgetary Educational Institution of Higher Education N. P. Ogarev Mordovia State University, Saransk, Russian Federation
🇷🇺
Federal State Budgetary Educational Institution of Higher Education Kirov State Medical University of Ministry of Health of the Russian Federation, Kirov, Russian Federation
🇷🇺
Professorskaya Klinika LLC, Perm, Russian Federation

and more 7 locations

The Long Non Coding MALAT1 as a Potential Salivary Diagnostic Biomarker in Oral Squamous Cell Carcinoma Through Targeting mi RNA 124

Completed

Conditions: Oral Squamous Cell Carcinoma

First Posted Date: 2023-02-01

Last Posted Date: 2023-09-13

Lead Sponsor: Fayoum University

Target Recruit Count: 40

Registration Number: NCT05708209

Locations: 🇪🇬
Rania Hassan Shalby, Giza, Egypt

A Study to Learn About a Modified RNA Vaccine Against Shingles in Healthy Adults

Phase 2

Active, not recruiting

Conditions: Human
Herpes Zoster Infection
Shingles

Interventions: Biological: Shingrix

First Posted Date: 2023-01-30

Last Posted Date: 2025-05-13

Lead Sponsor: Pfizer

Target Recruit Count: 900

Registration Number: NCT05703607

Locations: 🇺🇸
CTI Clinical Research Center, Cincinnati, Ohio, United States
🇺🇸
DM Clinical Research, Martin Diagnostic Clinic, Tomball, Texas, United States
🇺🇸
Tri-City Cardiology, Gilbert, Arizona, United States

and more 32 locations

Aschistosoma Haematobiumspecific microRNAas a Tumor Marker for Early Diagnosis and Prognosis of Bilharzial Bladder Cancer in Eygpt

Not Applicable

Not yet recruiting

Conditions: Bladder Cancer

Interventions: Diagnostic Test: urinary micro RNA detection

First Posted Date: 2023-01-25

Last Posted Date: 2023-01-25

Lead Sponsor: Sohag University

Target Recruit Count: 50

Registration Number: NCT05697224

Barrett's Esophagus and Esophageal Adenocarcinoma, Searching for Reliable Diagnostic RNA Plasma-based Biomarkers

Recruiting

Conditions: Esophageal Neoplasms

First Posted Date: 2023-01-18

Last Posted Date: 2024-07-17

Lead Sponsor: University Hospital, Ghent

Target Recruit Count: 100

Registration Number: NCT05688176

Locations: 🇧🇪
University hospital Ghent, Ghent, Oost-Vlaanderen, Belgium

Relation Between MicroRNA 203 and 210 and Sparing the Laparoscopic Examination in Cases of Unexplained Infertility

Not Applicable

Completed

Conditions: Infertility Unexplained
Endometriosis

Interventions: Procedure: Laparoscopic Exploration
Diagnostic Test: Estimation of Plasma Expression level of MICRO RNA 203 & 210

First Posted Date: 2023-01-11

Last Posted Date: 2023-01-11

Lead Sponsor: Benha University

Target Recruit Count: 100

Registration Number: NCT05680350

Locations: 🇪🇬
Banha University, Banhā, El- Qalyobia, Egypt

Single-cell RNA Sequencing Resolves the Regulatory Role of HBV on the Hepatocellular Carcinoma Immune Microenvironment

Recruiting

Conditions: Primary Liver Cancer
HBV

Interventions: Diagnostic Test: HBV DNA Sequencing

First Posted Date: 2023-01-10

Last Posted Date: 2023-01-10

Lead Sponsor: Fubing Wang

Target Recruit Count: 20

Registration Number: NCT05677724

Locations: 🇨🇳
Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China

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