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Interest of High-throughput Sequencing of RNAs for the Diagnosis of Heterogeneous Genetic Diseases
- Conditions
- DNA SequencingDiagnosis of Genetic Diseases of Heterogeneous Origin
- Interventions
- Genetic: RNA sequencing
- First Posted Date
- 2019-06-03
- Last Posted Date
- 2019-06-03
- Lead Sponsor
- University Hospital, Strasbourg, France
- Target Recruit Count
- 15
- Registration Number
- NCT03971292
- Locations
- 🇫🇷
Les Hôpitaux Universitaires de Strasbourg, Strasbourg, France
Primary Resistance in HIV Patients in Colombia
Completed
- Conditions
- HIV Infection
- Interventions
- Diagnostic Test: HIV-1 plasma RNA Genotyping secuencing by Sanger techniqueDiagnostic Test: HIV-1 plasma RNA Genotyping secuencing by Ultra-deep sequencing technique
- First Posted Date
- 2019-05-21
- Last Posted Date
- 2025-02-19
- Lead Sponsor
- Fundacion REVIVA, Red de VIH del Valle del Cauca
- Target Recruit Count
- 527
- Registration Number
- NCT03957369
- Locations
- 🇨🇴
REVIVA, Red de VIH del Valle del Cauca, Cali, Valle, Colombia
Macroscopic and Molecular Changes in Knee Muscular-tendon Unit in Response to Acute Resistant Load
Not Applicable
- Conditions
- Quadriceps Muscle
- Interventions
- Behavioral: Background QuestionnaireOther: Acute resistant load exercisesOther: Pain QuestionnaireGenetic: DNA and RNA testDiagnostic Test: UltrasoundDiagnostic Test: Percutaneous Needle Core Biopsy
- First Posted Date
- 2019-05-15
- Last Posted Date
- 2019-05-15
- Lead Sponsor
- Hillel Yaffe Medical Center
- Target Recruit Count
- 300
- Registration Number
- NCT03950596
- Locations
- 🇮🇱
Hillel Yaffe Medical Center, Hadera, Israel
Micro RNA as Prediction and/or Prognostic Markers of IRIS in TB-HIV Co-infected Patients
- Conditions
- HIV InfectionTuberculosis Infection
- Interventions
- Other: Detection of molecular Biomarkers
- First Posted Date
- 2019-05-07
- Last Posted Date
- 2020-01-07
- Lead Sponsor
- ANRS, Emerging Infectious Diseases
- Target Recruit Count
- 134
- Registration Number
- NCT03941210
- Locations
- 🇰🇭
Institut Pasteur du Cambodge, Phnom Penh, Cambodia
DNA Exome Sequencing TCM for Sjögren's Syndrome
- Conditions
- Sjögren's Syndrome
- Interventions
- Diagnostic Test: DNA Exome sequencingDiagnostic Test: Oral microbiomeDiagnostic Test: ProteomicsDiagnostic Test: RNA sequencingDiagnostic Test: CytokineDiagnostic Test: Traditional Chinese Medicine patternDiagnostic Test: Traditional Chinese Medicine tongue diagnosisDiagnostic Test: Traditional Chinese Medicine pulse diagnosisDiagnostic Test: Heart rate variabilityDiagnostic Test: Schirmer's testDiagnostic Test: Blood function test, liver function test, kidney function test, and immune function test
- First Posted Date
- 2019-05-02
- Last Posted Date
- 2019-05-06
- Lead Sponsor
- Taipei Veterans General Hospital, Taiwan
- Target Recruit Count
- 40
- Registration Number
- NCT03935373
- Locations
- 🇨🇳
Ching-Mao Chang, Taipei, Taiwan (r.o.c.), Taiwan
Serum HBV RNA Value on Chronic Hepatitis B Virus Infection Manage
Completed
- Conditions
- Drug WithdrawalChronic HBV Infection
- Interventions
- Diagnostic Test: serum HBV RNA
- First Posted Date
- 2019-04-09
- Last Posted Date
- 2021-02-02
- Lead Sponsor
- Changhai Hospital
- Target Recruit Count
- 454
- Registration Number
- NCT03909191
Network Medicine, Epigenetics and Obesity
- Conditions
- ObesityType2 Diabetes
- Interventions
- Other: DNA methylome and total RNA sequencing
- First Posted Date
- 2019-04-04
- Last Posted Date
- 2019-09-18
- Lead Sponsor
- University of Campania "Luigi Vanvitelli"
- Target Recruit Count
- 100
- Registration Number
- NCT03903757
Study on High-risk MDS Patients Based on RNA-seq Technology
- Conditions
- MDS
- First Posted Date
- 2019-04-04
- Last Posted Date
- 2019-04-22
- Lead Sponsor
- Zhejiang Provincial Hospital of TCM
- Target Recruit Count
- 120
- Registration Number
- NCT03903055
- Locations
- 🇨🇳
ZJHTCM, Hangzhou, Zhejiang, China
Evaluation of Dried Blood Spot for HCV RNA Testing
Not Applicable
Completed
- Conditions
- Hepatitis C, Chronic
- Interventions
- Diagnostic Test: Abbott RealTime HCV assay from DBSDiagnostic Test: HCV for use on the cobas® 6800/8800 Systems from PSC and DBSDiagnostic Test: Aptima® HCV Quant Dx Assay from DBSDiagnostic Test: HCV for use on the cobas® 4800Systems from PSC and DBS
- First Posted Date
- 2019-03-29
- Last Posted Date
- 2020-12-17
- Lead Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
- Target Recruit Count
- 942
- Registration Number
- NCT03896087
- Locations
- 🇬🇷
Hellenic Scientific Society for the Study of AIDS and Sexually Transmitted Diseases, Athens, Greece
🇨🇲Centre Pasteur du Cameroun, Yaoundé, Yaounde, Cameroon
🇬🇪National Centre for Disease Control, Tbilisi, Georgia
The TOGETHER Project - Kidney RNA-seq Validation
Completed
- Conditions
- Kidney Transplant Rejection
- First Posted Date
- 2019-03-14
- Last Posted Date
- 2022-09-19
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 302
- Registration Number
- NCT03874299
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States