Risperidone
- Generic Name
- Risperidone
- Brand Names
- Perseris, Risperdal, Rykindo, Uzedy, Okedi
- Drug Type
- Small Molecule
- Chemical Formula
- C23H27FN4O2
- CAS Number
- 106266-06-2
- Unique Ingredient Identifier
- L6UH7ZF8HC
- Background
Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone).
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- Indication
Risperidone is indicated for the treatment of schizophrenia and irritability associated with autistic disorder. It is also indicated as monotherapy, or adjunctly with lithium or valproic acid, for the treatment of acute mania or mixed episodes associated with bipolar I disorder.
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- Associated Conditions
- Acute Mania, Irritability, Mixed manic depressive episode, Psychosis, Schizophrenia, Acute Manic episode, Agitated psychotic state
- Associated Therapies
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Depakote ER Plus an Atypical Antipsychotic Vs. an Atypical Antipsychotic Alone in the Treatment of Schizophrenia
- Conditions
- First Posted Date
- 2003-11-18
- Last Posted Date
- 2006-08-04
- Lead Sponsor
- Abbott
- Target Recruit Count
- 400
- Registration Number
- NCT00073164
Atypical Neuroleptic Drugs in People With Mental Retardation/Developmental Delay
- Conditions
- First Posted Date
- 2003-07-22
- Last Posted Date
- 2005-06-24
- Target Recruit Count
- 50
- Registration Number
- NCT00065273
- Locations
- 🇺🇸
University of Kansas, Lawrence, Kansas, United States
Study of Outcome and Safety of Lithium, Divalproex and Risperidone for Mania in Children and Adolescents
- Conditions
- Interventions
- First Posted Date
- 2003-04-08
- Last Posted Date
- 2013-04-04
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 379
- Registration Number
- NCT00057681
- Locations
- 🇺🇸
University of Pittsburgh/WPIC, Pittsburgh, Pennsylvania, United States
🇺🇸Johns Hopkins Medical Center, Baltimore, Maryland, United States
🇺🇸Children's National Medical Center, Washington, District of Columbia, United States
Risperidone Treatment in Schizophrenia Patients Who Are Currently Taking Clozapine
- First Posted Date
- 2003-03-17
- Last Posted Date
- 2019-10-01
- Lead Sponsor
- University of Maryland, Baltimore
- Target Recruit Count
- 65
- Registration Number
- NCT00056498
- Locations
- 🇺🇸
Maryland Psychiatric Research Center, Catonsville, Maryland, United States
Treatment of Early Onset Schizophrenia Spectrum Disorders (TEOSS)
- Conditions
- Interventions
- First Posted Date
- 2003-02-05
- Last Posted Date
- 2014-03-26
- Lead Sponsor
- University of North Carolina, Chapel Hill
- Target Recruit Count
- 116
- Registration Number
- NCT00053703
- Locations
- 🇺🇸
University of Washington, Seattle, Washington, United States
🇺🇸University of North Carolina, Chapel Hill, North Carolina, United States
🇺🇸Cambridge Health Alliance, Medford, Massachusetts, United States
Schizophrenia Study In Adults
- Conditions
- First Posted Date
- 2002-11-18
- Last Posted Date
- 2017-08-16
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 231
- Registration Number
- NCT00049946
- Locations
- 🇺🇸
GSK Clinical Trial Call Center, Terrell, Texas, United States
Treatment and Outcome of Early Onset Bipolar Disorder
- Conditions
- First Posted Date
- 2002-11-13
- Last Posted Date
- 2014-01-22
- Lead Sponsor
- Northwell Health
- Target Recruit Count
- 40
- Registration Number
- NCT00048802
- Locations
- 🇺🇸
The Zucker Hillside Hospital, Long Island Jewish Medical Center, Glen Oaks, New York, United States
Switching Medication to Treat Schizophrenia
- Conditions
- Interventions
- First Posted Date
- 2002-09-05
- Last Posted Date
- 2016-04-28
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Target Recruit Count
- 219
- Registration Number
- NCT00044655
A Study of the Effectiveness and Safety of Risperidone to Augment SSRI Therapy in Patients With Treatment-resistant Depression
- Conditions
- First Posted Date
- 2002-09-05
- Last Posted Date
- 2011-05-18
- Target Recruit Count
- 258
- Registration Number
- NCT00044681
The Efficacy and Safety of Risperidone in the Treatment of Adolescents With Schizophrenia
- Conditions
- First Posted Date
- 2002-05-03
- Last Posted Date
- 2011-06-08
- Target Recruit Count
- 279
- Registration Number
- NCT00034749
Drug Development Updates
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