Benzatropine
- Generic Name
- Benzatropine
- Brand Names
- Cogentin
- Drug Type
- Small Molecule
- Chemical Formula
- C21H25NO
- CAS Number
- 86-13-5
- Unique Ingredient Identifier
- 1NHL2J4X8K
- Background
Benztropine, with the chemical formula 3alpha-diphenylmethoxytropane, is a tropane-based dopamine inhibitor used for the symptomatic treatment of Parkinson's disease. It is a combination molecule between a tropane ring, similar to cocaine, and a diphenyl ether from the dialkylpiperazines determined to be a dopamine uptake inhibitor since 1970. The generation...
- Indication
用于治疗帕金森病。也用于药物引起的锥体外系疾患，口服1小时起效，肌肉或静脉注射数分钟内起效，作用持续24小时。具有抗胆碱及抗组胺作用，并有轻度局部麻醉作用。
- Associated Conditions
- Parkinsonism
- Associated Therapies
- -
Comparison of Optimal Antipsychotic Treatments for Adults With Schizophrenia
- Conditions
- Interventions
- First Posted Date
- 2008-12-04
- Last Posted Date
- 2013-02-08
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 21
- Registration Number
- NCT00802100
- Locations
- 🇺🇸
Medical College of Georgia, Augusta, Georgia, United States
🇺🇸University of Texas Southwestern Medical Center, Dallas, Texas, United States
🇺🇸SHANTI Clinical Trials, Colton, California, United States
Anticholinergic Burden in Schizophrenia
- Conditions
- Interventions
- First Posted Date
- 2008-07-15
- Last Posted Date
- 2015-08-24
- Lead Sponsor
- Centre for Addiction and Mental Health
- Target Recruit Count
- 2
- Registration Number
- NCT00715377
- Locations
- 🇨🇦
Centre for Addiction and Mental Health, Toronto, Ontario, Canada
A Comparison Study of the Efficacy of Quetiapine and Haloperidol in Agitated Adults in Emergency Room
- Conditions
- Interventions
- First Posted Date
- 2007-04-06
- Last Posted Date
- 2019-07-26
- Lead Sponsor
- University of Southern California
- Target Recruit Count
- 72
- Registration Number
- NCT00457366
- Locations
- 🇺🇸
Los Angeles County Hospital, Los Angeles, California, United States
A Phase II/III Double-Blind Study of Amitriptyline and Mexiletine for Painful Neuropathy in HIV Infection
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-10-29
- Target Recruit Count
- 240
- Registration Number
- NCT00000793
- Locations
- 🇺🇸
UCLA CARE Center CRS, Los Angeles, California, United States
🇺🇸Hosp. of the Univ. of Pennsylvania CRS, Philadelphia, Pennsylvania, United States
🇺🇸Northwestern University CRS, Chicago, Illinois, United States
Effect of Antidepressants on Back Pain
- Conditions
- Interventions
- First Posted Date
- 2001-07-05
- Last Posted Date
- 2012-06-05
- Lead Sponsor
- US Department of Veterans Affairs
- Target Recruit Count
- 130
- Registration Number
- NCT00018200
- Locations
- 🇺🇸
VA San Diego Healthcare System, San Diego, San Diego, California, United States
Evaluation of Benztropine for Cocaine Craving - 2
- Conditions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2017-02-24
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Registration Number
- NCT00000333
- Locations
- 🇺🇸
Washington DC VA, Washington, District of Columbia, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.