Fluoxetine
- Generic Name
- Fluoxetine
- Brand Names
- Prozac, Sarafem, Symbyax
- Drug Type
- Small Molecule
- Chemical Formula
- C17H18F3NO
- CAS Number
- 54910-89-3
- Unique Ingredient Identifier
- 01K63SUP8D
- Background
Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI). It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies.
- Indication
Fluoxetine is indicated for both acute and maintenance treatment of major depressive disorder, obsessive compulsive disorder, and bulimia nervosa; however, it is only indicated for acute treatment of panic disorder independent of whether agoraphobia is present. Fluoxetine may also be used in combination with olanzapine to treat depression related to Bipolar ...
- Associated Conditions
- Alcohol Dependency, Anorexia Nervosa (AN), Bulimia Nervosa, Cataplexy, Depression, Major Depressive Disorder (MDD), Major depressive disorder, recurrent episode, Myoclonus, Obesity, Obsessive Compulsive Disorder (OCD), Panic Disorder With Agoraphobia, Panic disorder without agoraphobia, Premature Ejaculation, Premenstrual Dysphoric Disorder (PMDD)
- Associated Therapies
- Maintenance therapy
Prozac Treatment of Major Depression: Discontinuation Study
- Conditions
- First Posted Date
- 2007-01-26
- Last Posted Date
- 2011-12-15
- Lead Sponsor
- New York State Psychiatric Institute
- Target Recruit Count
- 627
- Registration Number
- NCT00427128
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇺🇸New York State Psychiatric Institute, New York, New York, United States
Efficacy of Seroquel SR in Combination With an Antidepressant in Treatment of Major Depressive Disorder
- Conditions
- First Posted Date
- 2006-07-13
- Last Posted Date
- 2011-01-26
- Lead Sponsor
- AstraZeneca
- Target Recruit Count
- 494
- Registration Number
- NCT00351910
- Locations
- 🇸🇪
Research Site, Uppsala, Sweden
Antidepressant Medication Plus Directly Observed Therapy for Improving Adherence to Antiretroviral Therapy
- Conditions
- Interventions
- First Posted Date
- 2006-06-20
- Last Posted Date
- 2013-11-15
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 150
- Registration Number
- NCT00338767
- Locations
- 🇺🇸
UCSF Market Street Study Site, San Francisco, California, United States
Treatment of Hypochondriasis With CBT and/or SSRI
- Conditions
- Interventions
- First Posted Date
- 2006-06-20
- Last Posted Date
- 2017-04-25
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 195
- Registration Number
- NCT00339079
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
🇺🇸Columbia Medical Center, New York Psychiatric Institute, New York City, New York, United States
Determining Optimal Continuation Treatment Duration for Depressed Children and Adolescents
- Conditions
- First Posted Date
- 2006-06-02
- Last Posted Date
- 2014-01-08
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 200
- Registration Number
- NCT00332787
- Locations
- 🇺🇸
Children's Medical Center at Dallas, Outpatient Psychiatry Clinic, Dallas, Texas, United States
Dichotic Listening as a Predictor of Medication Response in Depression
- Conditions
- Interventions
- First Posted Date
- 2006-02-27
- Last Posted Date
- 2019-05-30
- Lead Sponsor
- New York State Psychiatric Institute
- Target Recruit Count
- 25
- Registration Number
- NCT00296725
- Locations
- 🇺🇸
Depression Evaluation Service, New York State Psychiatric Institute, New York, New York, United States
Fluoxetine to Prevent Relapse and Enhance Psychological Recovery in Women With Anorexia Nervosa
- Conditions
- Interventions
- First Posted Date
- 2006-02-08
- Last Posted Date
- 2017-12-13
- Lead Sponsor
- New York State Psychiatric Institute
- Target Recruit Count
- 93
- Registration Number
- NCT00288574
- Locations
- 🇺🇸
New York State Psychiatric Institute/Columbia University Medical Center, New York, New York, United States
Improving Sleep and Psychological Functioning in People With Depression and Insomnia
- Conditions
- Interventions
- First Posted Date
- 2005-11-02
- Last Posted Date
- 2018-08-28
- Lead Sponsor
- Wake Forest University Health Sciences
- Target Recruit Count
- 60
- Registration Number
- NCT00247624
- Locations
- 🇺🇸
Wake Forest University Health Sciences; Department of Psychiatry and Behavioral Medicine, Winston-Salem, North Carolina, United States
Fluoxetine in Pediatric Body Dysmorphic Disorder
- First Posted Date
- 2005-10-28
- Last Posted Date
- 2018-04-27
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 43
- Registration Number
- NCT00245635
- Locations
- 🇺🇸
Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, United States
🇺🇸Rhode Island Hospital, Providence, Rhode Island, United States
Maintenance Interpersonal Psychotherapy for Sustaining Remission of Depression
- Conditions
- First Posted Date
- 2005-09-28
- Last Posted Date
- 2013-06-25
- Lead Sponsor
- University of Pittsburgh
- Target Recruit Count
- 93
- Registration Number
- NCT00227981
- Locations
- 🇺🇸
Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, United States
Drug Development Updates
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