Vancomycin
- Generic Name
- Vancomycin
- Brand Names
- Firvanq, Vancocin
- Drug Type
- Small Molecule
- Chemical Formula
- C66H75Cl2N9O24
- CAS Number
- 1404-90-6
- Unique Ingredient Identifier
- 6Q205EH1VU
- Background
Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.
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- Indication
Administered intravenously, vancomycin is indicated in adult and pediatric patients for the treatment of septicemia, infective endocarditis, skin and skin structure infections, bone infections, and lower respiratory tract infections. Administered orally, vancomycin is indicated in adult and pediatric patients for the treatment of Clostridium difficile-associ...
- Associated Conditions
- Clostridium Difficile Associated Diarrhea (CDAD), Enterocolitis caused by Staphylococcus aureus, Infection caused by staphylococci, Severe Staphylococcal infection
- Associated Therapies
- -
First Time Right of Vancomycin
- First Posted Date
- 2023-07-27
- Last Posted Date
- 2023-07-27
- Lead Sponsor
- Erasmus Medical Center
- Target Recruit Count
- 134
- Registration Number
- NCT05964114
Intra-wound Vancomycin Powder for Prevention of Surgical Site Infection Following Spinal Surgery
- First Posted Date
- 2023-07-25
- Last Posted Date
- 2024-11-27
- Lead Sponsor
- Rabin Medical Center
- Target Recruit Count
- 363
- Registration Number
- NCT05959603
- Locations
- 🇮🇱
Rabin Medical Center, Petah tikva, Israel
Lyophilized Fecal Microbiome Transfer vs. Vancomycin Monotherapy for Primary Clostridioides Difficile Infection
- Conditions
- Interventions
- First Posted Date
- 2023-02-02
- Last Posted Date
- 2024-04-10
- Lead Sponsor
- Rambam Health Care Campus
- Target Recruit Count
- 196
- Registration Number
- NCT05709184
- Locations
- 🇭🇺
University of Debrecen, Debrecen, Hungary
🇮🇱Rambam Health Care Campus, Haifa, Israel
🇬🇧Imperial College of London, London, United Kingdom
LocalVancomycinPowderToPreventPeriprostheticJointInfection.
- Conditions
- Interventions
- First Posted Date
- 2023-01-26
- Last Posted Date
- 2023-02-10
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 174
- Registration Number
- NCT05697965
Impact of Prophylactic Antibiotics on Bloodstream Infections After Liberation From Extracorporeal Membrane Oxygenation
- First Posted Date
- 2022-12-15
- Last Posted Date
- 2022-12-15
- Lead Sponsor
- Universität des Saarlandes
- Target Recruit Count
- 42
- Registration Number
- NCT05651464
- Locations
- 🇩🇪
University Hospital of Saarland, Homburg, Saarland, Germany
The Effect of Intrawound Vancomycin Powder on Surgical Site Infection in Inguinal Lymph Node Dissection
- First Posted Date
- 2022-11-22
- Last Posted Date
- 2023-12-05
- Lead Sponsor
- Women and Infants Hospital of Rhode Island
- Target Recruit Count
- 30
- Registration Number
- NCT05625373
- Locations
- 🇺🇸
Women and Infants Hospital, Providence, Rhode Island, United States
Vancomycin Study in Multiple Sclerosis (MS)
- First Posted Date
- 2022-09-14
- Last Posted Date
- 2024-03-22
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Target Recruit Count
- 12
- Registration Number
- NCT05539729
- Locations
- 🇺🇸
Corinne Goldsmith Dickinson Center for Multiple Sclerosis at Mount Sinai, New York, New York, United States
Model-informed Precision Dosing of Vancomycin in Adults
- Conditions
- Interventions
- First Posted Date
- 2022-09-10
- Last Posted Date
- 2023-12-01
- Lead Sponsor
- University Hospital, Ghent
- Target Recruit Count
- 155
- Registration Number
- NCT05535075
- Locations
- 🇧🇪
Ghent University Hospital, Ghent, Belgium
🇧🇪General Hospital Sint-Jan Brugge, Brugge, Belgium
Efficacy of Diluted Betadine vs Antibiotic Installation Before Surgical Wound Closure in Prevention of Post Cardiac Surgery Wound Infection
- First Posted Date
- 2022-03-11
- Last Posted Date
- 2022-03-11
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 80
- Registration Number
- NCT05276687
Prevention of C.Difficile Infections With Oral Vancomycine in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant
- Conditions
- Interventions
- First Posted Date
- 2022-02-25
- Last Posted Date
- 2022-02-25
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 336
- Registration Number
- NCT05256693
Drug Development Updates
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