MedPath

Selurampanel

Generic Name
Selurampanel
Drug Type
Small Molecule
Chemical Formula
C16H19N5O4S
CAS Number
912574-69-7
Unique Ingredient Identifier
7WG1MR7DAR
Background

Selurampanel has been investigated in Adrenocortical Adenoma and Sarcoma, Endometrial Stromal.

Medical Safety Follow-up Study for Patients Who Received More Than 28 Days of Total Exposure to BGG492

Phase 2
Completed
Conditions
Endometrial Stromal Sarcomas
Adrenocortical Adenoma
Interventions
Procedure: MRI, CT or ultrasound was permitted if MRI was contraindicated
Procedure: Dexamethasone Supression Test
Procedure: Sonogram
Procedure: Biopsy
First Posted Date
2014-05-29
Last Posted Date
2016-12-05
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
59
Registration Number
NCT02150213
Locations
🇸🇰

Novartis Investigative Site, Banska Bystrica, Slovakia

Efficacy of 5 Weeks of Treatment With BGG492 in Patients With Spasticity Due to Multiple Sclerosis

Phase 2
Withdrawn
Conditions
Muscle Spasticity Due to Multiple Sclerosis
Interventions
Drug: Placebo
First Posted Date
2012-07-25
Last Posted Date
2017-04-20
Lead Sponsor
Novartis Pharmaceuticals
Registration Number
NCT01649050

A Randomized,Double Blind, Placebo Controlled Study to Assess Efficacy,Safety and Tolerability of BGG492 in Migraine Prevention

Phase 2
Withdrawn
Conditions
Patients With Migraine Equal of /More Than 3 and Equal of/ Less Than 12 Migraine Attacks/4 Weeks for Each of the Last 6 Months Preceding the Screening
Interventions
Drug: Placebo
First Posted Date
2012-06-13
Last Posted Date
2017-04-20
Lead Sponsor
Novartis Pharmaceuticals
Registration Number
NCT01617941

Phase II BGG492 Capsule Extension for Partial Epilepsy

Phase 2
Completed
Conditions
Partial Onset Seizures
Interventions
First Posted Date
2011-04-20
Last Posted Date
2021-03-05
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
56
Registration Number
NCT01338805
Locations
🇸🇰

Novartis Investigative Site, Kosice, Slovakia

Study of BGG492 in Patients With Chronic Subjective Tinnitus

Phase 2
Completed
Conditions
Chronic Subjective Tinnitus
Interventions
First Posted Date
2011-02-24
Last Posted Date
2017-03-22
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
96
Registration Number
NCT01302873
Locations
🇳🇱

Novartis Investigative Site, Groningen, Netherlands

Evaluate the Efficacy of BGG492 as Adjunctive Treatment in Patients With Refractory Partial Onset Seizures

Phase 2
Withdrawn
Conditions
Partial Onset Seizures
Interventions
Drug: Placebo
First Posted Date
2010-07-22
Last Posted Date
2012-05-01
Lead Sponsor
Novartis
Registration Number
NCT01167335
Locations
🇺🇸

Johns Hopkins Hospital, Baltimore, Maryland, United States

🇺🇸

Epilepsy Care Specialists, S.C., Milwaukee, Wisconsin, United States

🇪🇸

Novartis Investigative Site, Barcelona, Spain

and more 2 locations

Efficacy and Safety of BGG492 in the Treatment of Migraine

Phase 2
Completed
Conditions
Migraine
Interventions
First Posted Date
2009-05-04
Last Posted Date
2020-12-17
Lead Sponsor
Novartis
Target Recruit Count
75
Registration Number
NCT00892203
Locations
🇺🇸

California Clinical Trials, 1560 Chevy Chase Drive, Suite 140, Glendale, California, United States

🇺🇸

California Clinical Trials, 15625 Lakewood Boulevard, Paramount, California, United States

🇩🇪

Novartis Investigator Site, Munich, Germany

and more 1 locations

Effect of BGG492 on EEG in Patients With Photosensitive Epilepsy

Phase 2
Completed
Conditions
Photosensitive Epilepsy
Interventions
Drug: Placebo
First Posted Date
2008-11-02
Last Posted Date
2016-09-23
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
13
Registration Number
NCT00784212
Locations
🇩🇪

Novartis Investigator Site, Radeberg, Germany

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